Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 9/20 | 0.56 |
| ▸ | DRD3 | P35462 | 6/20 | 0.56 |
| ▸ | DRD4 | P21917 | 5/20 | 0.56 |
| ▸ | KDR | P35968 | 2/20 | 0.49 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | PDE5A | O76074 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | PTAFR | P25105 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | PDE1A | P54750 | 1/20 | 0.47 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11061374 | 0.95 | KDR (0.51) | DRD2DRD3DRD4KDRPDE3B | |
| SCHEMBL10668573 | 0.78 | DRD3 (0.71) | DRD2DRD3DRD4HRH3 | |
| SCHEMBL11070987 | 0.78 | DRD2 (0.60) | DRD2DRD3DRD4HTR7 | |
| SCHEMBL11062767 | 0.78 | MAOA (0.66) | DRD2DRD3DRD4 | |
| SCHEMBL11064059 | 0.76 | HRH3 (0.46) | HRH3HTR7 | |
| SCHEMBL23097703 | 0.75 | DRD2 (0.72) | DRD2DRD3DRD4ALDH1A1HPGD | |
| SCHEMBL23097707 | 0.75 | DRD3 (0.62) | DRD2DRD3DRD4HRH3 | |
| SCHEMBL11065503 | 0.75 | OPRM1 (0.53) | HTR7 | |
| SCHEMBL23097661 | 0.75 | DRD3 (0.65) | DRD2DRD3DRD4HRH3 | |
| SCHEMBL11073538 | 0.74 | HTR7 (0.45) | DRD2DRD3DRD4HRH3HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4482560-A | Carbostyril derivatives, and antihistaminic agents containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-11-13 | — | — | US | disclosed |