Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MMP9 | P14780 | 6/20 | 0.32 |
| ▸ | MMP2 | P08253 | 5/20 | 0.32 |
| ▸ | MMP8 | P22894 | 4/20 | 0.32 |
| ▸ | MMP13 | P45452 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | OGT | O15294 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
| ▸ | PYGB | P11216 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Barbital SCHEMBL43818 | 0.71 | LMNA (1.00) | LMNATP53ALDH1A1MMP9MMP2 | |
| Barbital SCHEMBL3859278 | 0.71 | LMNA (1.00) | LMNATP53ALDH1A1MMP9MMP2 | |
| Barbital SCHEMBL11305876 | 0.69 | LMNA (0.71) | LMNATP53ALDH1A1MMP9MMP2 | |
| Barbital SCHEMBL4525046 | 0.69 | LMNA (0.81) | LMNATP53ALDH1A1MMP9MMP2 | |
| Barbital SCHEMBL11319317 | 0.69 | LMNA (0.94) | LMNATP53ALDH1A1MMP9MMP2 | |
| Barbital SCHEMBL236590 | 0.69 | LMNA (0.94) | LMNATP53ALDH1A1MMP9MMP2 | |
| Barbital SCHEMBL11328256 | 0.69 | LMNA (0.94) | LMNATP53ALDH1A1MMP9MMP2 | |
| Barbital SCHEMBL2128102 | 0.69 | LMNA (0.94) | LMNATP53ALDH1A1MMP9MMP2 | |
| Barbital SCHEMBL11212132 | 0.69 | LMNA (0.94) | LMNATP53ALDH1A1MMP9MMP2 | |
| Barbital SCHEMBL11328233 | 0.69 | LMNA (0.94) | LMNATP53ALDH1A1MMP9MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4456715-A | BASRBITURIC ACID-MELAMINE REACTION PRODUCT | BAYER AKTIENGESELLSCHAFT (DE) | 1984-06-26 | — | — | US | disclosed |