Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.81 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 6/20 | 0.36 |
| ▸ | MMP2 | P08253 | 5/20 | 0.36 |
| ▸ | MMP8 | P22894 | 5/20 | 0.36 |
| ▸ | MMP13 | P45452 | 4/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Barbital SCHEMBL43818 | 0.90 | LMNA (1.00) | LMNATP53ALDH1A1HSD17B10KDM4E | |
| Barbital SCHEMBL3859278 | 0.90 | LMNA (1.00) | LMNATP53ALDH1A1HSD17B10KDM4E | |
| Barbital SCHEMBL2128102 | 0.87 | LMNA (0.94) | LMNATP53ALDH1A1HSD17B10KDM4E | |
| Barbital SCHEMBL7592317 | 0.87 | LMNA (0.94) | LMNATP53ALDH1A1HSD17B10KDM4E | |
| Barbital SCHEMBL11328233 | 0.87 | LMNA (0.94) | LMNATP53ALDH1A1HSD17B10KDM4E | |
| Barbital SCHEMBL23533431 | 0.87 | LMNA (0.94) | LMNATP53ALDH1A1HSD17B10KDM4E | |
| Barbital SCHEMBL236590 | 0.87 | LMNA (0.94) | LMNATP53ALDH1A1HSD17B10KDM4E | |
| Barbital SCHEMBL11328256 | 0.87 | LMNA (0.94) | LMNATP53ALDH1A1HSD17B10KDM4E | |
| Barbital SCHEMBL21084914 | 0.87 | LMNA (0.94) | LMNATP53ALDH1A1HSD17B10KDM4E | |
| Barbital SCHEMBL21084955 | 0.87 | LMNA (0.94) | LMNATP53ALDH1A1HSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7541385-B2 | Bronchodilating β-agonist compositions and methods | MYLAN TECHNOLOGIES, INC. | 2009-06-02 | — | — | US | disclosed |
| US-20070166236-A1 | BRONCHODILATING BETA-AGONIST COMPOSITIONS AND METHODS | DEY, L.P. (US) | 2007-07-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070166236-A1 | BRONCHODILATING BETA-AGONIST COMPOSITIONS AND METHODS | ADRB2, ADRB3, ADRB1 | LMNA 1033/4885TP53 4799/4885ALDH1A1 2085/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.