Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | ERN1 | O75460 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PRKDC | P78527 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28513765 | 0.80 | MAPT (0.42) | CYP3A4MAPTALDH1A1KDM4ETDP1 | |
| SCHEMBL547660 | 0.78 | CYP3A4 (0.56) | CYP3A4MAPTALDH1A1KDM4ETDP1 | |
| SCHEMBL25342401 | 0.74 | PRKDC (0.40) | ALDH1A1KDM4ETDP1KMT2AMEN1 | |
| SCHEMBL6854010 | 0.72 | AKR1B1 (0.43) | ALDH1A1KDM4ETDP1KMT2AMEN1 | |
| SCHEMBL13894661 | 0.71 | ALDH1A1 (0.43) | CYP3A4MAPTALDH1A1KDM4ETDP1 | |
| SCHEMBL11928782 | 0.71 | HSD17B10 (0.36) | MAPTALDH1A1KDM4ETDP1AKR1B1 | |
| SCHEMBL548164 | 0.70 | CYP3A4 (0.47) | CYP3A4MAPTALDH1A1KDM4ETDP1 | |
| SCHEMBL29818737 | 0.70 | PRKDC (0.40) | MAPTALDH1A1KDM4ETDP1KMT2A | |
| SCHEMBL27481246 | 0.70 | HSD17B10 (0.49) | CYP3A4MAPTALDH1A1KDM4ETDP1 | |
| SCHEMBL24136726 | 0.70 | ALDH1A1 (0.42) | CYP3A4MAPTALDH1A1KDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-59163378-A | — | — | None | — | — | JP | disclosed |
| JP-S59163378-A | GLADIOLIC ACID DERIVATIVE AND PLANT GROWTH REGULATOR | TEIJIN LTD | 1984-09-14 | — | — | JP | disclosed |
| US-4344956-A | Oxotetrahydrothiophenes | ERCOLI NICOLO | 1982-08-17 | — | — | US | disclosed |