SCHEMBL547660

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL11061567	0.78	CYP3A4 (0.45)	CYP3A4MAPTALDH1A1KDM4ETDP1
	SCHEMBL548164	0.77	CYP3A4 (0.47)	CYP3A4MAPTACHEALDH1A1KDM4E
	SCHEMBL604701	0.74	ALDH1A1 (0.41)	CYP3A4MAPTALDH1A1KDM4ETDP1
	SCHEMBL10701039	0.74	CYP3A4 (0.58)	CYP3A4MAPTACHEALDH1A1KDM4E
	SCHEMBL243902	0.74	ERN1 (0.52)	CYP3A4MAPTACHEALDH1A1KDM4E
	SCHEMBL547661	0.73	CYP3A4 (0.47)	CYP3A4MAPTACHEALDH1A1KDM4E
	SCHEMBL547850	0.73	ALDH1A1 (0.39)	CYP3A4MAPTALDH1A1KDM4ETDP1
	Haematommic Acid SCHEMBL13495709	0.72	CYP3A4 (1.00)	CYP3A4MAPTACHEALDH1A1KDM4E
	SCHEMBL598164	0.71	CYP3A4 (0.53)	CYP3A4MAPTACHEALDH1A1KDM4E
	SCHEMBL27452224	0.71	ERN1 (0.52)	CYP3A4MAPTALDH1A1KDM4ETDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.