SCHEMBL548164

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL27792972	0.81	CYP3A4 (0.47)	CYP3A4MAPTCYP19A1L3MBTL1ALDH1A1
	SCHEMBL11413711	0.81	CYP3A4 (0.56)	CYP3A4MAPTCYP19A1L3MBTL1ALDH1A1
	SCHEMBL7154020	0.78	CYP1A2 (0.39)	CYP3A4MAPTL3MBTL1POLBALDH1A1
	SCHEMBL547660	0.77	CYP3A4 (0.56)	CYP3A4MAPTCYP19A1L3MBTL1POLB
	SCHEMBL14577383	0.75	ERN1 (0.46)	CYP3A4MAPTALDH1A1TSHRERN1
	SCHEMBL548044	0.74	ALDH1A1 (0.46)	CYP3A4MAPTALDH1A1TDP1TSHR
	SCHEMBL2320182	0.74	ALDH1A1 (0.54)	CYP3A4MAPTCYP19A1L3MBTL1POLB
	SCHEMBL10685105	0.74	POLB (0.41)	CYP3A4MAPTCYP19A1L3MBTL1POLB
	SCHEMBL3392120	0.73	TDP1 (0.48)	CYP3A4MAPTL3MBTL1ALDH1A1TDP1
	SCHEMBL548031	0.73	ERN1 (0.36)	CYP3A4MAPTCYP19A1L3MBTL1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.