Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | THRB | P10828 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | PTGIR | P43119 | 4/20 | 0.37 |
| ▸ | STS | P08842 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Temefos SCHEMBL44105 | 0.98 | LMNA (0.53) | LMNASMN1; SMN2ALDH1A1CYP3A4HSD17B10 | |
| Temefos SCHEMBL23303378 | 0.98 | LMNA (0.53) | LMNASMN1; SMN2ALDH1A1CYP3A4HSD17B10 | |
| Temefos SCHEMBL6388031 | 0.96 | LMNA (0.51) | LMNASMN1; SMN2ALDH1A1CYP3A4HSD17B10 | |
| Temefos SCHEMBL10455340 | 0.91 | LMNA (0.47) | LMNASMN1; SMN2ALDH1A1CYP3A4HSD17B10 | |
| Temefos SCHEMBL15553439 | 0.91 | LMNA (0.51) | LMNASMN1; SMN2ALDH1A1CYP3A4HSD17B10 | |
| SCHEMBL30412917 | 0.86 | CYP3A4 (0.53) | LMNASMN1; SMN2ALDH1A1CYP3A4HSD17B10 | |
| Temefos SCHEMBL9193178 | 0.85 | LMNA (0.54) | LMNASMN1; SMN2ALDH1A1CYP3A4HSD17B10 | |
| SCHEMBL11061618 | 0.84 | ALDH1A1 (0.57) | LMNASMN1; SMN2ALDH1A1CYP3A4HSD17B10 | |
| Temefos SCHEMBL20919592 | 0.84 | ALDH1A1 (0.46) | LMNASMN1; SMN2ALDH1A1CYP3A4HSD17B10 | |
| Temefos SCHEMBL9809762 | 0.84 | LMNA (0.42) | LMNASMN1; SMN2ALDH1A1CYP3A4HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0663103-A4 | HIGH EFFICIENCY SOLAR PHOTOVOLTAIC CELLS PRODUCED WITH INEXPENSIVE MATERIALS BY PROCESSES SUITABLE FOR LARGE VOLUME PRODUCTION. | MOWLES THOMAS A (US) | 1997-10-15 | — | — | EP | claimed |
| EP-0663103-A1 | HIGH EFFICIENCY SOLAR PHOTOVOLTAIC CELLS PRODUCED WITH INEXPENSIVE MATERIALS BY PROCESSES SUITABLE FOR LARGE VOLUME PRODUCTION | MOWLES, Thomas, A. (US) | 1995-07-19 | — | — | EP | claimed |
| WO-1994007268-A1 | HIGH EFFICIENCY SOLAR PHOTOVOLTAIC CELLS PRODUCED WITH INEXPENSIVE MATERIALS BY PROCESSES SUITABLE FOR LARGE VOLUME PRODUCTION | MOWLES THOMAS A (US) | 1994-03-31 | — | — | WO | claimed |