Temefos

Temefos

SCHEMBL44105

COP(=S)(OC)Oc1ccc(Sc2ccc(OP(=S)(OC)OC)cc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.53
SMN1; SMN2 Q16637 4/20 0.53
ALDH1A1 P00352 3/20 0.53
CYP3A4 P08684 3/20 0.53
HSD17B10 Q99714 3/20 0.53
MAPK1 P28482 2/20 0.53
THRB P10828 2/20 0.53
TP53 P04637 1/20 0.53
TSHR P16473 2/20 0.50
PTGIR P43119 4/20 0.38
STS P08842 4/20 0.35
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
TDP1 Q9NUW8 1/20 0.33
GAA P10253 1/20 0.33
HPGD P15428 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
HAO1 Q9UJM8 1/20 0.33
MAPT P10636 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Temefos SCHEMBL23303378 1.00 LMNA (0.53) LMNASMN1; SMN2ALDH1A1CYP3A4HSD17B10
Temefos SCHEMBL8741692 0.98 LMNA (0.51) LMNASMN1; SMN2ALDH1A1CYP3A4HSD17B10
Temefos SCHEMBL6388031 0.98 LMNA (0.51) LMNASMN1; SMN2ALDH1A1CYP3A4HSD17B10
Temefos SCHEMBL10455340 0.93 LMNA (0.47) LMNASMN1; SMN2ALDH1A1CYP3A4HSD17B10
Temefos SCHEMBL15553439 0.93 LMNA (0.51) LMNASMN1; SMN2ALDH1A1CYP3A4HSD17B10
SCHEMBL30412917 0.88 CYP3A4 (0.53) LMNASMN1; SMN2ALDH1A1CYP3A4HSD17B10
Temefos SCHEMBL9193178 0.87 LMNA (0.54) LMNASMN1; SMN2ALDH1A1CYP3A4HSD17B10
SCHEMBL11061618 0.86 ALDH1A1 (0.57) LMNASMN1; SMN2ALDH1A1CYP3A4HSD17B10
Temefos SCHEMBL9809762 0.85 LMNA (0.42) LMNASMN1; SMN2ALDH1A1CYP3A4HSD17B10
Temefos SCHEMBL20919592 0.85 ALDH1A1 (0.46) LMNASMN1; SMN2ALDH1A1CYP3A4HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 25996 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026105160-A1 NOVEL AGROCHEMICAL COMPOSITION COMPRISING 3-SUBSTITUTED PHENYLAMIDINE COMPOUNDS AND USE THEREOF PI INDUSTRIES LTD. (IN) 2026-05-21 WO claimed
US-20260137082-A1 FUNGICIDAL COMPOSITIONS COMPRISING FLUDIOXONIL SYNGENTA CROP PROTECTION AG (CH) 2026-05-21 US claimed
CN-122055165-A Combination treatment of prostate cancer with two bispecific antibodies 詹森生物科技公司 2026-05-15 CN claimed
EP-4345366-B1 STRIP-SHAPED LAMP AND END COVER FOR SUCH A STRIP-SHAPED LAMP SELF ELECTRONICS CO LTD (CN) 2026-05-06 EP claimed
EP-4723893-A2 COMPOSITIONS AND METHODS TO MITIGATE PHYTOTOXIC EFFECTS OF AGRICHEMICALS Ascribe Bioscience Inc. (US) 2026-04-15 EP claimed
EP-3175865-B1 FUNCTIONAL PARTICLES, PROCESS TO OBTAIN THEM, AND THEIR APPLICATIONS SMART INOVATION LDA (PT) 2026-04-15 EP claimed
EP-4198627-B1 LIGHT SUPPLEMENTING LAMP FOR HEMISPHERICAL CAMERA AND HEMISPHERICAL CAMERA HANGZHOU HIKVISION DIGITAL TEC (CN) 2026-04-15 EP claimed
EP-4719059-A1 INCREASED PALATABILITY OF INSECTICIDAL INSECT BAITS Bio Logic Crop Science, S.L. (ES) 2026-04-08 EP claimed
EP-4521083-B1 COLOR MATCHING OBSERVATION BOX FOR LED STANDARD LIGHT SOURCE WENZHOU JIAYI INSTR CO LTD (CN) 2026-04-08 EP claimed
EP-3800968-B1 SMART CONTROL DEVICE FOR LIGHT FIXTURE Suzhou opple lighting co ltd (CN) 2026-04-08 EP claimed
US-4439779-A Serial dot printer for office machines ING. C. OLIVETTI & C., S.P.A. (IT) 1984-03-27 US claimed
EP-0092993-A2 Composition for investigating alimentary functions A/S Alfred Benzon (DK) 1983-11-02 EP claimed
WO-1983002417-A1 DEVICE FOR SANDPAPERING AND/OR SHELLING WOODEN PARTS CIAUDO, Claude, José, Louis 1983-07-21 WO claimed
US-4387087-A RADIOLOGY; DIAGNOSIS/MEDICAL/ RESEARCH CORPORATION (US) 1983-06-07 US claimed
EP-0068297-A1 A new insecticidal composition, processes for its production and its use A. Nattermann & Cie. GmbH (DE) 1983-01-05 EP claimed
EP-0038756-A2 Cationic lipophilic complexes of 99m Tc useful for myocardial and hepatobiliary imaging Research Corporation (US) 1981-10-28 EP claimed
EP-0036739-A2 Serial dot printer for office machines Ing. C. Olivetti & C., S.p.A. (IT) 1981-09-30 EP claimed
WO-1981000253-A1 MODIFICATION OF CHARACTERISTICS OF ANIMAL BLOOD AFTER SLAUGHTERING BALSSE C (FR) 1981-02-05 WO claimed
EP-0016894-A2 Divan-chair having arms, backrest and legs foldable on the plane of its seat CARLIN DI BOLZICCO DINO (IT) 1980-10-15 EP claimed
US-3968207-A O,O,O',O'-TETRAMETHYL-O,O'-THIODI-P-PHENYLENE PHOSPHOROTHIOATE AMERICAN CYANAMID COMPANY (US) 1976-07-06 US claimed