SCHEMBL11061894

SCHEMBL11061894

Cc1cccc(C)c1OP(Oc1ccccc1)Oc1c(C)cccc1C

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SCN4A P35499 6/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
TSHR P16473 4/20 0.36
ACHE P22303 2/20 0.36
CA4 P22748 1/20 0.36
LMNA P02545 3/20 0.35
ALOX12 P18054 1/20 0.35
KDM4E B2RXH2 1/20 0.34
ALDH1A1 P00352 1/20 0.34
HPGD P15428 1/20 0.34
HSD17B10 Q99714 1/20 0.34
SCN8A Q9UQD0 3/20 0.34
KMT2A Q03164 2/20 0.33
SCN1A P35498 2/20 0.33
SCN5A Q14524 2/20 0.33
SCN9A Q15858 2/20 0.33
LTA4H P09960 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11332056 1.00 SCN4A (0.37) SCN4AL3MBTL1SMN1; SMN2TSHRACHE
SCHEMBL19160166 0.91 L3MBTL1 (0.40) SCN4AL3MBTL1TSHRACHELMNA
SCHEMBL25014057 0.88 ACHE (0.34) SCN4AL3MBTL1TSHRACHELMNA
SCHEMBL123568 0.87 CYP1A2 (0.41) SCN4AL3MBTL1SMN1; SMN2TSHRACHE
SCHEMBL11896439 0.86 L3MBTL1 (0.37) SCN4AL3MBTL1TSHRLMNAKDM4E
SCHEMBL10894088 0.84 ACHE (0.37) L3MBTL1SMN1; SMN2TSHRACHECA4
SCHEMBL10886728 0.84 ACHE (0.37) L3MBTL1SMN1; SMN2TSHRACHECA4
SCHEMBL28571280 0.79 DRD2 (0.41) SCN4ASMN1; SMN2TSHRACHECA4
SCHEMBL12810270 0.79 DRD2 (0.41) SCN4ASMN1; SMN2TSHRACHECA4
SCHEMBL13289 0.79 LTA4H (0.50) L3MBTL1TSHRACHECA4LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4456717-A PHOSPHITES AND SILOXANE-OXETANE COMPOUNDS BAYER AKTIENGESELLSCHAFT (DE) 1984-06-26 US disclosed
EP-0096818-A1 Stabilizer combinations, their use in stabilizing thermoplastic polycarbonates, and stabilized thermoplastic polycarbonates BAYER AG (DE) 1983-12-28 EP disclosed