Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.40 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11060871 | 0.86 | NOTUM (0.38) | ALDH1A1L3MBTL1KDM4ETDP1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11061040 | 0.79 | ALDH1A1 (0.34) | ALDH1A1KDM4ETDP1SMN1; SMN2HPGD | |
| SCHEMBL11070298 | 0.77 | ALDH1A1 (0.41) | ALDH1A1L3MBTL1KDM4EHPGDHSD17B10 | |
| SCHEMBL29232190 | 0.76 | KDM4E (0.49) | ALDH1A1L3MBTL1NPSR1KDM4ETDP1 | |
| SCHEMBL890385 | 0.73 | PKM (0.56) | ALDH1A1KDM4ESMN1; SMN2HPGDHSD17B10 | |
| SCHEMBL11060856 | 0.69 | MAP4K4 (0.36) | ALDH1A1L3MBTL1KDM4EPOLBSMN1; SMN2 | |
| SCHEMBL11070521 | 0.68 | ALDH1A1 (0.47) | ALDH1A1NPSR1KDM4EPOLBSMN1; SMN2 | |
| SCHEMBL10967519 | 0.66 | HTT (0.47) | ALDH1A1L3MBTL1NPSR1KDM4ETDP1 | |
| SCHEMBL23725727 | 0.65 | KDM4E (0.43) | ALDH1A1L3MBTL1NPSR1KDM4ETDP1 | |
| SCHEMBL23725956 | 0.65 | KDM4E (0.50) | ALDH1A1L3MBTL1NPSR1KDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4490376-A | ANTIULCER AND SECRETORY AGENTS | FARMITALIA CARLO ERBA S.P.A (IT) | 1984-12-25 | — | — | US | disclosed |