Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 3/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | COMT | P21964 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | APLNR | P35414 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11062034 | 0.86 | ALDH1A1 (0.43) | L3MBTL1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL11070298 | 0.81 | ALDH1A1 (0.41) | L3MBTL1ALDH1A1KDM4EHPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL11061040 | 0.80 | ALDH1A1 (0.34) | ALDH1A1KDM4EHPGDHSD17B10SMN1; SMN2 | |
| SCHEMBL30132372 | 0.72 | PKM (0.57) | ALDH1A1KDM4EHPGDSMN1; SMN2KMT2A | |
| SCHEMBL11070521 | 0.72 | ALDH1A1 (0.47) | ALDH1A1KDM4EHPGDSMN1; SMN2NPC1 | |
| SCHEMBL11067252 | 0.66 | FABP3 (0.38) | ALDH1A1KDM4EHPGDHSD17B10MEN1 | |
| SCHEMBL11067299 | 0.65 | MEN1 (0.43) | ALDH1A1KDM4EHPGDHSD17B10SMN1; SMN2 | |
| SCHEMBL23726440 | 0.64 | METTL3 (0.46) | L3MBTL1ALDH1A1KDM4ESMN1; SMN2NPC1 | |
| SCHEMBL15603518 | 0.61 | L3MBTL1 (0.56) | NOTUMP2RX7L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL7190498 | 0.61 | SMN1; SMN2 (0.55) | NOTUMALDH1A1KDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4490376-A | ANTIULCER AND SECRETORY AGENTS | FARMITALIA CARLO ERBA S.P.A (IT) | 1984-12-25 | — | — | US | disclosed |