Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | PPIA | P62937 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10754382 | 0.86 | MAPT (0.46) | LMNAMAPTALDH1A1KDM4ENPC1 | |
| SCHEMBL10727527 | 0.85 | ALDH1A1 (0.47) | LMNAMAPTALDH1A1KDM4ENPC1 | |
| SCHEMBL10388184 | 0.85 | LMNA (0.46) | LMNAMAPTALDH1A1KDM4ENPC1 | |
| SCHEMBL10388680 | 0.84 | THRB (0.52) | LMNAMAPTTSHRHPGD | |
| SCHEMBL10753353 | 0.84 | KDM4E (0.44) | LMNAMAPTALDH1A1KDM4ENPC1 | |
| SCHEMBL11068978 | 0.84 | KDM4E (0.44) | LMNAMAPTALDH1A1KDM4ENPC1 | |
| SCHEMBL11113148 | 0.84 | ALDH1A1 (0.48) | LMNAMAPTALDH1A1KDM4ENPC1 | |
| SCHEMBL10667795 | 0.83 | GAA (0.45) | ALDH1A1TSHR | |
| SCHEMBL10846802 | 0.83 | GCK (0.46) | LMNAMAPTALDH1A1KDM4ENPC1 | |
| SCHEMBL10506794 | 0.83 | LMNA (0.44) | LMNAMAPTALDH1A1KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4425153-A | Herbicidal sulfonamides | E. I. DU PONT DE NEMOURS & CO. (US) | 1984-01-10 | — | — | US | disclosed |