Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | CXCL8 | P10145 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.39 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | CFTR | P13569 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.37 |
| ▸ | UGT1A9 | O60656 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.37 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.37 |
| ▸ | ALB | P02768 | 1/20 | 0.37 |
| ▸ | UGT1A6 | P19224 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycine SCHEMBL27900643 | 0.85 | TSHR (0.62) | TSHRPOLBAKR1B1CXCL8RECQL | |
| Acetoacetic Acid SCHEMBL11499670 | 0.85 | ALDH1A1 (0.61) | TSHRPOLBAKR1B1ALDH1A1KDM4E | |
| Acetic Acid SCHEMBL7836902 | 0.85 | TSHR (0.68) | TSHRPOLBAKR1B1RECQLALDH1A1 | |
| Bicarbonate SCHEMBL28650787 | 0.80 | TSHR (0.75) | TSHRPOLBAKR1B1RECQLALDH1A1 | |
| O-Tolylamine SCHEMBL11500268 | 0.80 | CYP3A4 (0.54) | RECQLERCC5FEN1ALDH1A1CFTR | |
| Questiomycin B SCHEMBL11499299 | 0.80 | ALOX15 (0.56) | TSHRAKR1B1RECQLALDH1A1CFTR | |
| Acetoacetic Acid SCHEMBL11499836 | 0.80 | ALDH1A1 (0.44) | TSHRAKR1B1RECQLALDH1A1CFTR | |
| O-Tolylamine SCHEMBL5679561 | 0.80 | CYP3A4 (0.54) | RECQLERCC5FEN1ALDH1A1CFTR | |
| Acetoacetic Acid SCHEMBL11807425 | 0.79 | TSHR (0.57) | TSHRPOLBRECQLERCC5FEN1 | |
| Acetoacetic Acid SCHEMBL11059298 | 0.79 | TSHR (0.57) | TSHRPOLBERCC5FEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4474609-A | Recrystallization-resistant monoazo pigment mixtures of high tinctorial strength, process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-10-02 | — | — | US | disclosed |
| US-4453942-A | Use of 1:2 cobalt complex dyes for dyeing leather or furs | CIBA-GEIGY CORPORATION (US) | 1984-06-12 | — | — | US | disclosed |
| US-4144231-A | Soluble trisazo dyestuffs containing a 2-phenyl-benzimidazolyl, -benzoxazolyl or -benzthiazolyl middle component | CASSELLA AKTIENGESELLSCHAFT (DE) | 1979-03-13 | — | — | US | disclosed |
| US-3971741-A | DISPERSION PIGMENTS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-07-27 | — | — | US | disclosed |