Benzene

Benzene

SCHEMBL11062753

NS(=O)(=O)c1cccc2ccccc12.c1ccccc1

nearest known ligand 0.96

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 6/20 0.96
CA1 P00915 6/20 0.96
CA9 Q16790 5/20 0.96
CDK2 P24941 1/20 0.59
F2 P00734 3/20 0.55
PRSS1 P07477 3/20 0.55
PRSS2 P07478 3/20 0.55
PRSS3 P35030 3/20 0.55
HTR6 P50406 1/20 0.55
LDHA P00338 1/20 0.53
CA12 O43570 3/20 0.50
CA4 P22748 2/20 0.50
CA6 P23280 2/20 0.50
CYP2C9 P11712 2/20 0.50
CA5A P35218 1/20 0.50
CA7 P43166 1/20 0.50
CA14 Q9ULX7 1/20 0.50
CA5B Q9Y2D0 1/20 0.50
HCRTR1 O43613 1/20 0.49
MEN1 O00255 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28464 0.98 CA2 (1.00) CA2CA1CA9CDK2F2
SCHEMBL29529240 0.98 CA2 (1.00) CA2CA1CA9CDK2F2
Hydrochloric Acid SCHEMBL951327 0.96 CA2 (0.96) CA2CA1CA9CDK2F2
Hydrochloric Acid SCHEMBL8125684 0.94 CA2 (0.92) CA2CA1CA9CDK2F2
Phosphoric Acid SCHEMBL28841729 0.88 CA2 (0.81) CA2CA1CA9CDK2F2
Acetamide SCHEMBL28617889 0.87 CA2 (0.79) CA2CA1CA9CDK2F2
Isothiocyanate SCHEMBL28619475 0.87 CA2 (0.79) CA2CA1CA9CDK2F2
SCHEMBL3149642 0.86 CA2 (0.78) CA2CA1CA9CDK2F2
Pyrrolidine SCHEMBL17599458 0.84 CA1 (0.73) CA2CA1CA9CDK2F2
SCHEMBL9138970 0.84 CDK2 (0.78) CA2CA1CA9CDK2LDHA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4464452-A NEGATIVE CHARGE ENHANCER XEROX CORPORATION (US) 1984-08-07 US disclosed