Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.73 |
| ▸ | CA9 | Q16790 | 2/20 | 0.73 |
| ▸ | CA2 | P00918 | 2/20 | 0.73 |
| ▸ | PNMT | P11086 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CDK2 | P24941 | 1/20 | 0.47 |
| ▸ | HTR6 | P50406 | 6/20 | 0.45 |
| ▸ | F2 | P00734 | 2/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.45 |
| ▸ | LDHA | P00338 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.42 |
| ▸ | CCR2 | P41597 | 2/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.42 |
| ▸ | CIT | O14578 | 1/20 | 0.42 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29529240 | 0.86 | CA2 (1.00) | CA1CA9CA2MEN1KMT2A | |
| SCHEMBL28464 | 0.86 | CA2 (1.00) | CA1CA9CA2MEN1KMT2A | |
| Benzene SCHEMBL11062753 | 0.84 | CA2 (0.96) | CA1CA9CA2MEN1KMT2A | |
| SCHEMBL27901054 | 0.84 | CA2 (0.96) | CA1CA9CA2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL951327 | 0.84 | CA2 (0.96) | CA1CA9CA2MEN1KMT2A | |
| Ammonia Solution, Strong SCHEMBL28028391 | 0.84 | CA2 (0.96) | CA1CA9CA2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8125684 | 0.82 | CA2 (0.92) | CA1CA9CA2MEN1KMT2A | |
| Phosphoric Acid SCHEMBL28841729 | 0.77 | CA2 (0.81) | CA1CA9CA2MEN1KMT2A | |
| Acetamide SCHEMBL28617889 | 0.76 | CA2 (0.79) | CA1CA9CA2CDK2HTR6 | |
| Isothiocyanate SCHEMBL28619475 | 0.76 | CA2 (0.79) | CA1CA9CA2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110511170-A | A kind of synthetic method of chirality nafoxidine -3- carboxylic acid | HANGZHOU ALLSINO BIOTECHNOLOGY CO LTD | 2019-11-29 | — | — | CN | disclosed |
| EP-2997966-A1 | Naphthyl Sulfonamide Pyrrolidine Derivatives as KEAP-1 Modulators for the Treatment of Diabetes, Obesity, Dyslipidemia and Related Disorders | SANOFI (FR) | 2016-03-23 | — | — | EP | disclosed |
| EP-2997966-A1 | Naphthyl Sulfonamide Pyrrolidine Derivatives as KEAP-1 Modulators for the Treatment of Diabetes, Obesity, Dyslipidemia and Related Disorders | SANOFI (FR) | 2016-03-23 | — | — | EP | disclosed |