SCHEMBL11062896

SCHEMBL11062896

Nc1c(Cl)cc(S(=O)(=O)C(F)(F)F)cc1Cl

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 8/20 0.57
CA1 P00915 7/20 0.57
CA9 Q16790 7/20 0.57
ALDH1A1 P00352 3/20 0.50
POLB P06746 1/20 0.47
APEX1 P27695 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
EPAS1 Q99814 5/20 0.41
CYP3A4 P08684 1/20 0.41
LMNA P02545 2/20 0.39
CA12 O43570 2/20 0.38
CA4 P22748 2/20 0.38
CA6 P23280 2/20 0.38
CA5A P35218 2/20 0.38
CA7 P43166 2/20 0.38
CA14 Q9ULX7 2/20 0.38
CA5B Q9Y2D0 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7750645 0.90 ALDH1A1 (0.55) CA2CA1CA9ALDH1A1POLB
SCHEMBL698013 0.88 CA2 (0.53) CA2CA1CA9ALDH1A1POLB
SCHEMBL697141 0.84 CA2 (0.53) CA2CA1CA9ALDH1A1POLB
SCHEMBL10499080 0.83 ALDH1A1 (0.44) CA2CA1CA9ALDH1A1MEN1
SCHEMBL7752783 0.82 ALDH1A1 (0.46) CA2CA1CA9ALDH1A1TDP1
SCHEMBL698382 0.81 CA2 (0.50) CA2CA1CA9ALDH1A1POLB
SCHEMBL697097 0.80 CA1 (0.48) CA2CA1CA9POLBAPEX1
SCHEMBL10497555 0.79 MEN1 (0.42) CA2CA1CA9ALDH1A1MEN1
SCHEMBL1881348 0.79 ALDH1A1 (0.70) CA2CA1CA9ALDH1A1POLB
SCHEMBL1334378 0.77 ALDH1A1 (0.54) CA2CA1ALDH1A1POLBMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4459304-A MITICIDES, NEMATOCIDES, FUNGICIDES, BACTERICIDES, INSECTICIDES BAYER AKTIENGESELLSCHAFT (DE) 1984-07-10 US disclosed
EP-0000156-B1 2-ARYLAMINO-3,5-DINITRO-BENZOTRIFLUORIDES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS PESTICIDES. BAYER AG (DE) 1980-11-12 EP disclosed
EP-0004642-A1 Diaryl amines, process for their preparation and their use BAYER AG (DE) 1979-10-17 EP disclosed
EP-0000156-A1 2-Arylamino-3,5-dinitro-benzotrifluorides, process for their preparation and their use as pesticides. BAYER AG (DE) 1979-01-10 EP disclosed