Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | VCAM1 | P19320 | 3/20 | 0.46 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.42 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.42 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7745986 | 0.83 | ALDH1A1 (0.51) | ALDH1A1VCAM1EPAS1PTPN1CYP3A4 | |
| SCHEMBL7769087 | 0.83 | VCAM1 (0.50) | ALDH1A1VCAM1CYP3A4L3MBTL1F2 | |
| SCHEMBL11062896 | 0.82 | CA2 (0.57) | ALDH1A1EPAS1TDP1CYP3A4LMNA | |
| SCHEMBL1368288 | 0.80 | VCAM1 (0.63) | ALDH1A1VCAM1EPAS1PTPN1LMNA | |
| SCHEMBL205303 | 0.78 | ALDH1A1 (0.70) | ALDH1A1EPAS1TDP1CYP3A4HPGD | |
| SCHEMBL7750645 | 0.77 | ALDH1A1 (0.55) | ALDH1A1EPAS1TDP1CYP3A4LMNA | |
| SCHEMBL5786092 | 0.76 | ALDH1A1 (0.64) | ALDH1A1EPAS1PTPN1TDP1CYP3A4 | |
| SCHEMBL10705569 | 0.76 | EPAS1 (0.38) | ALDH1A1VCAM1EPAS1PTPN1TDP1 | |
| SCHEMBL11684790 | 0.76 | VCAM1 (0.66) | ALDH1A1VCAM1EPAS1LMNAMAPT | |
| SCHEMBL17482143 | 0.75 | ALDH1A1 (0.53) | ALDH1A1VCAM1TDP1CYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0597304-B1 | Use of substituted benzimidazoles for combating parasitic protozoas | BAYER AG (DE) | 2001-01-10 | — | — | EP | disclosed |
| US-5877195-A | INSECTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1999-03-02 | — | — | US | disclosed |
| US-5863933-A | NEMATOCIDES, PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1999-01-26 | — | — | US | disclosed |
| EP-0596358-B1 | 0-Phenylenediamines containing fluoroakyl(ene) groups and their use as intermediates in the preparation of benzimidazoles | BAYER AG (DE) | 1998-10-28 | — | — | EP | disclosed |
| EP-0667863-B1 | 2-PERHALOGENALKYL-SUBSTITUTED BENZIMIDAZOLES, THEIR PREPARATION AND THEIR USE AS PESTICIDES | BAYER AG (DE) | 1998-06-03 | — | — | EP | disclosed |
| US-5656649-A | PESTICIDE, INSECTICIDES, NEMATOCIDE | BAYER AKTIENGESELLSCHAFT (DE) | 1997-08-12 | — | — | US | disclosed |
| US-5585395-A | INSECTICIDES, MITICIDES, FUNGICIDES, HERBICIDES, PLANT GROWTH REGULATORS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-12-17 | — | — | US | disclosed |
| US-5484953-A | CHEMICAL INTERMEDIATES FOR BENZIMIDAZOLES FOR INSECTICIDES OR NEMATOCIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-01-16 | — | — | US | disclosed |
| US-5482956-A | ANTIPROTOZOA AGENTS FOR ANIMALS OR INSECTS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-01-09 | — | — | US | disclosed |
| EP-0667862-A1 | 2-FLUOROALKYL-SUBSTITUTED BENZIMIDAZOLES, THEIR PREPARATION AND THEIR USE AS PESTICIDES | BAYER AG (DE) | 1995-08-23 | — | — | EP | disclosed |
| EP-0667863-A1 | 2-PERHALOGENALKYL-SUBSTITUTED BENZIMIDAZOLES, THEIR PREPARATION AND THEIR USE AS PESTICIDES | BAYER AG (DE) | 1995-08-23 | — | — | EP | disclosed |
| EP-0667861-A1 | 2-FLUOROALKYL-SUBSTITUTED BENZIMIDAZOLES, THEIR PREPARATION AND THEIR USE AS PESTICIDES | BAYER AG (DE) | 1995-08-23 | — | — | EP | disclosed |
| WO-1994011349-A1 | 2-FLUOROALKYL-SUBSTITUTED BENZIMIDAZOLES, THEIR PREPARATION AND THEIR USE AS PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1994-05-26 | — | — | WO | disclosed |
| WO-1994011351-A1 | 2-PERHALOGENALKYL-SUBSTITUTED BENZIMIDAZOLES, THEIR PREPARATION AND THEIR USE AS PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1994-05-26 | — | — | WO | disclosed |
| WO-1994011350-A1 | 2-FLUOROALKYL-SUBSTITUTED BENZIMIDAZOLES, THEIR PREPARATION AND THEIR USE AS PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1994-05-26 | — | — | WO | disclosed |
| EP-0597304-A1 | Use of substituted benzimidazoles | BAYER AG (DE) | 1994-05-18 | — | — | EP | disclosed |
| EP-0596358-A1 | 0-Phenylenediamines containing fluoroakyl(ene) groups and their use as intermediates in the preparation of benzimidazoles | BAYER AG (DE) | 1994-05-11 | — | — | EP | disclosed |