Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 8/20 | 0.63 |
| ▸ | MMP2 | P08253 | 8/20 | 0.63 |
| ▸ | MMP9 | P14780 | 8/20 | 0.63 |
| ▸ | EGFR | P00533 | 9/20 | 0.61 |
| ▸ | MAOA | P21397 | 1/20 | 0.57 |
| ▸ | MAOB | P27338 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.52 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.51 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11063104 | 1.00 | MMP1 (0.63) | MMP1MMP2MMP9EGFRMAOA | |
| SCHEMBL10820794 | 0.84 | KDM4E (0.63) | MAPT | |
| SCHEMBL10492424 | 0.84 | MMP1 (0.80) | MMP1MMP2MMP9EGFRMAOA | |
| SCHEMBL10492426 | 0.84 | MMP1 (0.80) | MMP1MMP2MMP9EGFRMAOA | |
| SCHEMBL20657293 | 0.83 | HDAC1 (0.60) | MMP1MMP2MMP9EGFRMAOA | |
| SCHEMBL22772610 | 0.79 | MMP1 (0.52) | MMP1MMP2MMP9EGFRMAOA | |
| N-(2-Hydroxyphenyl)Cinnamamide SCHEMBL9989385 | 0.78 | MMP1 (1.00) | MMP1MMP2MMP9EGFRMAOA | |
| N-(2-Hydroxyphenyl)Cinnamamide SCHEMBL2305881 | 0.78 | MMP1 (1.00) | MMP1MMP2MMP9EGFRMAOA | |
| N-(2-Hydroxyphenyl)Cinnamamide SCHEMBL2305883 | 0.78 | MMP1 (1.00) | MMP1MMP2MMP9EGFRMAOA | |
| SCHEMBL1813156 | 0.78 | TGM2 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4455295-A | N-(p-Sulfophenyl) cinnamamide as sunscreen agent | HAARMANN & REIMER GMBH (DE) | 1984-06-19 | — | — | US | disclosed |