Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 10/20 | 1.00 |
| ▸ | MMP2 | P08253 | 10/20 | 1.00 |
| ▸ | MMP9 | P14780 | 10/20 | 1.00 |
| ▸ | NPC1 | O15118 | 3/20 | 0.73 |
| ▸ | RAB9A | P51151 | 3/20 | 0.73 |
| ▸ | MEN1 | O00255 | 2/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.73 |
| ▸ | EGFR | P00533 | 6/20 | 0.69 |
| ▸ | GAA | P10253 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 1/20 | 0.66 |
| ▸ | MAOA | P21397 | 1/20 | 0.64 |
| ▸ | MAOB | P27338 | 1/20 | 0.64 |
| ▸ | KDM1A | O60341 | 1/20 | 0.62 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.61 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.59 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.59 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| N-(2-Hydroxyphenyl)Cinnamamide SCHEMBL2305883 | 1.00 | MMP1 (1.00) | MMP1MMP2MMP9NPC1RAB9A | |
| N-(2-Hydroxyphenyl)Cinnamamide SCHEMBL2305881 | 1.00 | MMP1 (1.00) | MMP1MMP2MMP9NPC1RAB9A | |
| N-(2-Hydroxyphenyl)Cinnamamide SCHEMBL30311315 | 1.00 | MMP1 (1.00) | MMP1MMP2MMP9NPC1RAB9A | |
| SCHEMBL10492426 | 0.89 | MMP1 (0.80) | MMP1MMP2MMP9NPC1RAB9A | |
| SCHEMBL10492424 | 0.89 | MMP1 (0.80) | MMP1MMP2MMP9NPC1RAB9A | |
| SCHEMBL7771097 | 0.85 | MMP1 (0.73) | MMP1MMP2MMP9NPC1RAB9A | |
| SCHEMBL7771073 | 0.85 | MMP1 (0.73) | MMP1MMP2MMP9NPC1RAB9A | |
| SCHEMBL10737008 | 0.84 | MMP1 (1.00) | MMP1MMP2MMP9NPC1MEN1 | |
| SCHEMBL13675634 | 0.84 | MMP1 (0.72) | MMP1MMP2MMP9NPC1RAB9A | |
| SCHEMBL11575343 | 0.83 | MMP1 (0.71) | MMP1MMP2MMP9NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10457659-B2 | Compositions and methods for increasing proliferation of adult salivary stem cells | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2019-10-29 | — | — | US | disclosed |
| US-9370506-B2 | Modulators of aldehyde dehydrogenase and methods of use thereof | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2016-06-21 | — | — | US | disclosed |
| US-9370506-B2 | Modulators of aldehyde dehydrogenase and methods of use thereof | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2016-06-21 | — | — | US | disclosed |
| US-20150182506-A1 | Modulators of Aldehyde Dehydrogenase and Methods of Use Thereof | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2015-07-02 | — | — | US | disclosed |
| US-20150182506-A1 | Modulators of Aldehyde Dehydrogenase and Methods of Use Thereof | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2015-07-02 | — | — | US | disclosed |
| US-20140343045-A1 | Modulators of Aldehyde Dehydrogenase and Methods of Use Thereof | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2014-11-20 | — | — | US | disclosed |
| US-20140343045-A1 | Modulators of Aldehyde Dehydrogenase and Methods of Use Thereof | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2014-11-20 | — | — | US | disclosed |
| US-20140323520-A1 | Compositions and Methods for Increasing Proliferation of Adult Salivary Stem Cells | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2014-10-30 | — | — | US | disclosed |
| US-20140323520-A1 | Compositions and Methods for Increasing Proliferation of Adult Salivary Stem Cells | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2014-10-30 | — | — | US | disclosed |
| US-8772295-B2 | Modulators of aldehyde dehydrogenase and methods of use thereof | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2014-07-08 | — | — | US | disclosed |
| US-8529688-B2 | Phenolic compound and recording material | NIPPON SODA CO., LTD. (JP) | 2013-09-10 | — | — | US | disclosed |
| US-8389522-B2 | Modulators of aldehyde dehydrogenase and methods of use thereof | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2013-03-05 | — | — | US | disclosed |
| US-8389522-B2 | Modulators of aldehyde dehydrogenase and methods of use thereof | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2013-03-05 | — | — | US | disclosed |
| WO-2012149106-A1 | COMPOSITIONS AND METHODS FOR INCREASING PROLIFERATION OF ADULT SALIVARY STEM CELLS | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2012-11-01 | — | — | WO | disclosed |
| CN-102548768-A | Recording material using phenolic compound | NIPPON SODA CO | 2012-07-04 | — | — | CN | disclosed |
| US-20110308429-A1 | Phenolic compound and recording material | NIPPON SODA CO. LTD. (JP) | 2011-12-22 | — | — | US | disclosed |
| EP-2394985-A1 | PHENOLIC COMPOUND AND RECORDING MATERIAL | Nippon Soda Co., Ltd. (JP) | 2011-12-14 | — | — | EP | disclosed |
| WO-2010062308-A1 | MODULATORS OF ALDEHYDE DEHYDROGENASE AND METHODS OF USE THEREOF | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2010-06-03 | — | — | WO | disclosed |
| US-20100113423-A1 | Modulators of Aldehyde Dehydrogenase and Methods of Use Thereof | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2010-05-06 | — | — | US | disclosed |
| US-20100113423-A1 | Modulators of Aldehyde Dehydrogenase and Methods of Use Thereof | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2010-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140323520-A1 | Compositions and Methods for Increasing Proliferation of Adult Salivary Stem Cells | MKI67, ALDH1A1, ALDH1A2 | MMP1 518/4885MMP2 823/4885MMP9 2309/4885 |
| US-20140343045-A1 | Modulators of Aldehyde Dehydrogenase and Methods of Use Thereof | ALDH2, ALDH3A1, ALDH1A1 | MMP1 1612/4885MMP2 644/4885MMP9 1018/4885 |
| US-20150182506-A1 | Modulators of Aldehyde Dehydrogenase and Methods of Use Thereof | ALDH2, ALDH3A1, ALDH1A1 | MMP1 1612/4885MMP2 644/4885MMP9 1018/4885 |
| US-10457659-B2 | Compositions and methods for increasing proliferation of adult salivary stem cells | ALDH1A1, MKI67, ALDH1A2 | MMP1 1592/4885MMP2 974/4885MMP9 2474/4885 |
| US-20110308429-A1 | Phenolic compound and recording material | H1-4, H1-0, H1-3 | MMP1 371/4885MMP2 495/4885MMP9 596/4885 |
| US-20100113423-A1 | Modulators of Aldehyde Dehydrogenase and Methods of Use Thereof | ALDH2, ALDH3A1, ALDH1A1 | MMP1 1612/4885MMP2 644/4885MMP9 1018/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.