Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 4/20 | 0.50 |
| ▸ | MAOA | P21397 | 2/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
| ▸ | DRD4 | P21917 | 3/20 | 0.49 |
| ▸ | DRD2 | P14416 | 2/20 | 0.49 |
| ▸ | DRD3 | P35462 | 2/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.49 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11065044 | 0.90 | MAOA (0.61) | MAOAMAOBDRD4DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL11067443 | 0.89 | MAOA (0.60) | MAOAMAOBDRD4HRH3MEN1 | |
| SCHEMBL11065083 | 0.87 | MAOA (0.65) | KCNH2MAOAMAOBDRD4HRH3 | |
| SCHEMBL11073307 | 0.85 | MAOA (0.57) | MAOAMAOBDRD4DRD2DRD3 | |
| SCHEMBL11073435 | 0.84 | HTR7 (0.48) | MAOAMAOBDRD4DRD2DRD3 | |
| SCHEMBL10576436 | 0.84 | MAOA (0.63) | MAOAMAOBDRD4DRD2DRD3 | |
| SCHEMBL11073911 | 0.83 | SCN1A (0.60) | KCNH2DRD4DRD2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL11070539 | 0.83 | HTR7 (0.47) | MAOAMAOBDRD4DRD2DRD3 | |
| SCHEMBL6108202 | 0.80 | MAOA (0.58) | MAOAMAOBHRH3 | |
| SCHEMBL11073580 | 0.80 | MAOA (0.77) | MAOAMAOBDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4482560-A | Carbostyril derivatives, and antihistaminic agents containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-11-13 | — | — | US | disclosed |