Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.57 |
| ▸ | MAOB | P27338 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 6/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.55 |
| ▸ | DRD4 | P21917 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 2/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.51 |
| ▸ | HTR1A | P08908 | 2/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.48 |
| ▸ | HTR1D | P28221 | 1/20 | 0.48 |
| ▸ | HTR1B | P28222 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | HTR7 | P34969 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11065044 | 0.95 | MAOA (0.61) | MAOAMAOBMEN1KMT2AKDM4E | |
| SCHEMBL11065083 | 0.94 | MAOA (0.65) | MAOAMAOBMEN1KMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL11067443 | 0.94 | MAOA (0.60) | MAOAMAOBMEN1KMT2AKDM4E | |
| SCHEMBL11070939 | 0.90 | MAOA (0.52) | MAOAMAOBMEN1KMT2AKDM4E | |
| SCHEMBL11063504 | 0.85 | KCNH2 (0.50) | MAOAMAOBMEN1KMT2ADRD4 | |
| SCHEMBL11072939 | 0.84 | DRD4 (0.62) | MEN1KMT2ADRD4DRD2ADRB1 | |
| SCHEMBL11071304 | 0.84 | DRD4 (0.62) | MAOAMAOBMEN1KMT2ADRD4 | |
| SCHEMBL10570129 | 0.81 | DRD2 (0.55) | DRD4DRD2HTR1AHTR7DRD3 | |
| SCHEMBL11073435 | 0.80 | HTR7 (0.48) | MAOAMAOBMEN1KMT2ASIGMAR1 | |
| SCHEMBL10576436 | 0.80 | MAOA (0.63) | MAOAMAOBMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4482560-A | Carbostyril derivatives, and antihistaminic agents containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-11-13 | — | — | US | disclosed |