Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 3/20 | 0.38 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.37 |
| ▸ | FDPS | P14324 | 3/20 | 0.37 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.36 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7132650 | 0.87 | LMNA (0.33) | LMNA | |
| SCHEMBL15145074 | 0.81 | FAAH (0.45) | SMPD1ACE2GPR84FDPSSPHK1 | |
| SCHEMBL10926924 | 0.79 | SMPD1 (0.41) | SMPD1GPR84FDPSFFAR1ZDHHC7 | |
| SCHEMBL17457539 | 0.76 | SMPD1 (0.39) | SMPD1GPR84FDPSFFAR1ZDHHC7 | |
| SCHEMBL28522664 | 0.73 | OPRM1 (0.44) | SMPD1SPHK1LMNA | |
| SCHEMBL8210975 | 0.73 | OPRM1 (0.44) | SMPD1SPHK1LMNA | |
| SCHEMBL2851672 | 0.73 | OPRM1 (0.44) | SMPD1SPHK1LMNA | |
| SCHEMBL3795495 | 0.73 | OPRM1 (0.44) | SMPD1SPHK1LMNA | |
| SCHEMBL28693350 | 0.73 | OPRM1 (0.44) | SMPD1SPHK1LMNA | |
| SCHEMBL1792139 | 0.73 | FDPS (0.36) | SMPD1GPR84FDPSFFAR1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4452937-A | Ethylene polymer compositions stabilized against water treeing and electrical treeing by an organo titanium chelate; and the use thereof as insulation about electrical conductors | UNION CARBIDE CORPORATION (US) | 1984-06-05 | — | — | US | disclosed |