Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11464467 | 0.82 | SMN1; SMN2 (0.70) | NPSR1SMN1; SMN2MAPTGAAALDH1A1 | |
| SCHEMBL9335595 | 0.82 | HPGD (0.67) | POLBNPSR1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL5548239 | 0.82 | RAB9A (0.56) | POLBSMN1; SMN2MAPTGAAALDH1A1 | |
| SCHEMBL11059694 | 0.82 | CYP19A1 (0.48) | SMN1; SMN2MAPTGAANPC1RAB9A | |
| SCHEMBL9672872 | 0.81 | ADRA1A (0.59) | POLBNPSR1SMN1; SMN2MAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL8805273 | 0.81 | SMN1; SMN2 (0.68) | NPSR1SMN1; SMN2MAPTGAAALDH1A1 | |
| SCHEMBL9521689 | 0.80 | POLB (0.45) | POLBNPSR1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL21568080 | 0.77 | NPC1 (0.67) | POLBSMN1; SMN2MAPTGAAALDH1A1 | |
| SCHEMBL11457003 | 0.76 | SMN1; SMN2 (0.48) | POLBNPSR1SMN1; SMN2MAPTGAA | |
| SCHEMBL1503906 | 0.76 | ALDH1A1 (0.71) | POLBSMN1; SMN2MAPTGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4483707-A | PLANT SAFTENING AGENTS | CIBA-GEIGY CORPORATION (US) | 1984-11-20 | — | — | US | disclosed |