Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HASPIN | Q8TF76 | 6/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | FABP6 | P51161 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.40 |
| ▸ | CDK9 | P50750 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 2/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | CDK4 | P11802 | 1/20 | 0.40 |
| ▸ | CCND1 | P24385 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22810058 | 0.78 | PIM1 (0.61) | HASPINALDH1A1HPGDSMN1; SMN2CCNT1 | |
| SCHEMBL1594417 | 0.78 | PIM1 (0.61) | HASPINALDH1A1HPGDSMN1; SMN2CCNT1 | |
| SCHEMBL29625633 | 0.78 | HASPIN (0.59) | HASPINCCNT1CDK9PIM1 | |
| SCHEMBL11069044 | 0.76 | ALDH1A1 (0.57) | RAB9AALDH1A1HPGDSMN1; SMN2MEN1 | |
| SCHEMBL11071687 | 0.76 | HASPIN (0.48) | HASPINCCNT1CDK9PIM1 | |
| SCHEMBL9739332 | 0.75 | ACHE (0.57) | HASPINCCNT1CDK9PIM1 | |
| SCHEMBL677456 | 0.74 | ALK (0.47) | RAB9AALDH1A1POLBHPGDSMN1; SMN2 | |
| SCHEMBL29152717 | 0.71 | ATM (0.57) | RAB9AALDH1A1POLBHPGDSMN1; SMN2 | |
| SCHEMBL11826831 | 0.71 | KIT (0.64) | RAB9AALDH1A1POLBHPGDSMN1; SMN2 | |
| SCHEMBL24277019 | 0.70 | ACHE (0.73) | HASPINRAB9AALDH1A1POLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4483989-A | BENZOYLATION 6-HYDROXYCARBAZOLE, FORMYLATING, CYCLIZATION, AND SAPONIFICATION | AGENCE NATIONALE DE VALORISATION DE LA RECHERCHE (ANVAR) (FR) | 1984-11-20 | — | — | US | claimed |