Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 3/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11067562 | 0.92 | HTR7 (0.53) | DRD3HTR7DRD2DRD4KCNA3 | |
| SCHEMBL11070110 | 0.91 | S1PR5 (0.47) | DRD3HTR7DRD2DRD4OPRM1 | |
| SCHEMBL11071740 | 0.85 | HTR7 (0.50) | DRD3HTR7DRD2DRD4OPRK1 | |
| SCHEMBL11063139 | 0.85 | DRD3 (0.47) | DRD3HTR7DRD2DRD4KCNA3 | |
| SCHEMBL11070967 | 0.83 | DRD2 (0.53) | DRD3HTR7DRD2DRD4 | |
| SCHEMBL11064821 | 0.81 | MAOA (0.65) | DRD3DRD2DRD4 | |
| SCHEMBL11066559 | 0.81 | DRD2 (0.59) | DRD3HTR7DRD2DRD4 | |
| SCHEMBL11069074 | 0.81 | HTR7 (0.46) | DRD3HTR7DRD2DRD4OPRK1 | |
| SCHEMBL10572847 | 0.79 | EPHX2 (0.48) | DRD3DRD2DRD4OPRK1 | |
| SCHEMBL10570006 | 0.79 | KCNA5 (0.50) | DRD3DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4482560-A | Carbostyril derivatives, and antihistaminic agents containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-11-13 | — | — | US | disclosed |