Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 4/20 | 0.46 |
| ▸ | DRD4 | P21917 | 2/20 | 0.46 |
| ▸ | DRD3 | P35462 | 2/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SCN1A | P35498 | 1/20 | 0.41 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11071740 | 0.95 | HTR7 (0.50) | HTR7DRD2DRD4DRD3ADRB2 | |
| SCHEMBL11070967 | 0.94 | DRD2 (0.53) | HTR7DRD2DRD4DRD3SIGMAR1 | |
| SCHEMBL11070311 | 0.89 | ADRB2 (0.44) | HTR7DRD2DRD4DRD3ADRB2 | |
| SCHEMBL11063280 | 0.87 | DRD2 (0.53) | HTR7DRD2DRD4DRD3ADRB2 | |
| SCHEMBL11071326 | 0.86 | DRD2 (0.47) | HTR7DRD2DRD4DRD3ADRB2 | |
| SCHEMBL11071420 | 0.86 | DRD2 (0.47) | HTR7DRD2DRD4DRD3ADRB2 | |
| SCHEMBL11065769 | 0.86 | DRD2 (0.58) | HTR7DRD2DRD4DRD3ADRB2 | |
| SCHEMBL11064990 | 0.84 | DRD2 (0.51) | HTR7DRD2DRD4DRD3ADRB2 | |
| SCHEMBL11070769 | 0.84 | DRD2 (0.44) | HTR7DRD2DRD4DRD3ADRB2 | |
| SCHEMBL11068604 | 0.84 | KCNH2 (0.53) | HTR7DRD2DRD4DRD3HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4482560-A | Carbostyril derivatives, and antihistaminic agents containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-11-13 | — | — | US | disclosed |