Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10924387 | 0.86 | MEN1 (0.39) | LTA4HTSHRALOX5KDM4EALDH1A1 | |
| SCHEMBL11621874 | 0.83 | MERTK (0.41) | LTA4HTSHRMAPTKDM4EALDH1A1 | |
| SCHEMBL11552165 | 0.83 | LMNA (0.44) | MAPTKDM4EALDH1A1LMNAHTT | |
| SCHEMBL11484840 | 0.78 | F10 (0.39) | TSHRLMNASMN1; SMN2 | |
| SCHEMBL11468337 | 0.74 | SLC6A4 (0.33) | — | |
| SCHEMBL10926565 | 0.71 | TTR (0.42) | HSP90AA1MAPTHPGDLMNAPGR | |
| SCHEMBL10990216 | 0.69 | ADORA2A (0.49) | LTA4HTSHRMAPTKDM4EALDH1A1 | |
| SCHEMBL8779443 | 0.68 | ALDH1A1 (0.44) | LTA4HTSHRMAPTKDM4EALDH1A1 | |
| SCHEMBL5359429 | 0.67 | TDP1 (0.54) | PIN1LTA4HTSHRMAPTKDM4E | |
| SCHEMBL11217950 | 0.64 | ALDH1A1 (0.45) | PIN1LTA4HTSHRMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4450269-A | FUNGICIDES | FMC CORPORATION (US) | 1984-05-22 | — | — | US | disclosed |
| US-4201780-A | Mono-5-substituted-3-chloro-4H-1,2,6-thiadiazin-4-one antifungal agents | FMC CORPORATION (US) | 1980-05-06 | — | — | US | disclosed |
| US-4097594-A | Mono-5-substituted-3-chloro-4H-1,2,6-thiadiazin-4-one antifungal agents | FMC CORPORATION (US) | 1978-06-27 | — | — | US | disclosed |