Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 9/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.33 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 4/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.30 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11469586 | 0.86 | CXCL8 (0.35) | SLC6A4SLC6A2SLC6A3CXCL8HTR2A | |
| SCHEMBL11468336 | 0.74 | GLA (0.32) | NPBWR1 | |
| SCHEMBL10926565 | 0.70 | TTR (0.42) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL10926329 | 0.69 | MAPK1 (0.46) | NPBWR1 | |
| SCHEMBL4440731 | 0.69 | SLC6A4 (0.42) | SLC6A4SLC6A2SLC6A3CXCL8HTR2A | |
| Formaldehyde SCHEMBL28293005 | 0.68 | CXCL8 (0.42) | SLC6A4SLC6A2SLC6A3CXCL8HTR2A | |
| SCHEMBL7769553 | 0.67 | SLC6A2 (0.61) | SLC6A4SLC6A2SLC6A3CXCL8 | |
| SCHEMBL11621648 | 0.67 | LTA4H (0.44) | — | |
| SCHEMBL11552165 | 0.66 | LMNA (0.44) | — | |
| SCHEMBL10926616 | 0.65 | POLB (0.42) | SLC6A4HTR2AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4201780-A | Mono-5-substituted-3-chloro-4H-1,2,6-thiadiazin-4-one antifungal agents | FMC CORPORATION (US) | 1980-05-06 | — | — | US | disclosed |