Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 4/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | TYMS | P04818 | 1/20 | 0.35 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GSR | P00390 | 1/20 | 0.33 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11048493 | 1.00 | THRB (0.42) | THRBNFE2L2THRATYMSTRPM8 | |
| SCHEMBL28212448 | 0.81 | THRB (0.48) | THRBNFE2L2THRAMEN1KMT2A | |
| SCHEMBL11064205 | 0.78 | ELANE (0.41) | NFE2L2TRPM8MEN1KMT2ANPC1 | |
| SCHEMBL11064202 | 0.78 | ELANE (0.41) | NFE2L2TRPM8MEN1KMT2ANPC1 | |
| SCHEMBL28535471 | 0.74 | NFE2L2 (0.38) | NFE2L2TRPM8MEN1KMT2AALDH1A1 | |
| SCHEMBL25565205 | 0.74 | L3MBTL1 (0.47) | THRBTHRATYMSMEN1KMT2A | |
| SCHEMBL14530180 | 0.73 | ALDH1A1 (0.44) | THRBTHRATYMSALDH1A1KDM4E | |
| SCHEMBL29046996 | 0.72 | THRB (0.42) | THRBNFE2L2THRATYMSTRPM8 | |
| SCHEMBL27685619 | 0.72 | BACE1 (0.38) | THRBNFE2L2THRAMEN1KMT2A | |
| SCHEMBL18973455 | 0.72 | THRB (0.46) | THRBMEN1KMT2ANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4463169-A | Three component, carboxyl-containing compositions comprising dimercaptan | CIBA-GEIGY CORPORATION (US) | 1984-07-31 | — | — | US | disclosed |
| US-4439291-A | Acrylate-containing compositions and their polymerization | CIBA-GEIGY CORPORATION (US) | 1984-03-27 | — | — | US | disclosed |