Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1452726 | 0.97 | KDM4E (0.43) | KDM4EMAPTALOX15SMN1; SMN2 | |
| SCHEMBL8751009 | 0.97 | KDM4E (0.39) | KDM4EMAPTALOX15SMN1; SMN2 | |
| SCHEMBL10662588 | 0.97 | KDM4E (0.39) | KDM4EMAPTALOX15SMN1; SMN2 | |
| Water SCHEMBL10767439 | 0.95 | KDM4E (0.42) | KDM4EMAPTALOX15SMN1; SMN2 | |
| SCHEMBL4863025 | 0.89 | KDM4E (0.38) | KDM4EMAPTALOX15SMN1; SMN2 | |
| SCHEMBL4707720 | 0.81 | CA4 (0.34) | KDM4EMAPTALOX15SMN1; SMN2 | |
| SCHEMBL30583 | 0.75 | KDM4E (0.35) | KDM4EALOX15 | |
| SCHEMBL2717261 | 0.72 | — | — | |
| SCHEMBL963936 | 0.71 | — | — | |
| SCHEMBL5999991 | 0.71 | CA4 (0.35) | KDM4EMAPTALOX15SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4464398-A | BLEND OF QUATERNARY AMMONIUM SALTS | HUNTINGTON LABORATORIES, INC. (US) | 1984-08-07 | — | — | US | disclosed |
| US-4049585-A | BUILDERS, LOW SUDSING | THE PROCTER & GAMBLE COMPANY (US) | 1977-09-20 | — | — | US | disclosed |
| US-3979339-A | POLYVINYL PYRROLIDONE, VINYL ACETATE-VINYL ALCOHOL COPOLYMER | THE PROCTER & GAMBLE COMPANY (US) | 1976-09-07 | — | — | US | disclosed |
| US-3970594-A | SURFACTANT, BUILDER, POLYVINYL ALCOHOL OR PYRROLIDONE, POLYSACCHARIDE | THE PROCTER & GAMBLE COMPANY (US) | 1976-07-20 | — | — | US | disclosed |
| US-3950277-A | LIPASE ENZYME AND ACTIVATORS, ALKYLNAPHTHALENE SULFONATE | THE PROCTER & GAMBLE COMPANY (US) | 1976-04-13 | — | — | US | disclosed |
| US-3950260-A | SURFACTANTS | ELDIB ENGINEERING AND RESEARCH INC., | 1976-04-13 | — | — | US | disclosed |
| US-3936498-A | ALKANOYL ALKANOIC ACID OR SALT | OLIN CORPORATION (US) | 1976-02-03 | — | — | US | disclosed |