Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 3/20 | 0.50 |
| ▸ | SGMS2 | Q8NHU3 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 1/20 | 0.44 |
| ▸ | RXRG | P48443 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5400533 | 0.86 | SGMS2 (0.48) | MAPTL3MBTL1SGMS2MEN1KMT2A | |
| SCHEMBL9203023 | 0.84 | HTT (0.53) | SMN1; SMN2TDP1L3MBTL1SGMS2MEN1 | |
| SCHEMBL30468871 | 0.81 | SGMS2 (0.67) | MAPTCYP2C9CYP2C19SMN1; SMN2TDP1 | |
| SCHEMBL71081 | 0.81 | SGMS2 (0.67) | MAPTCYP2C9CYP2C19SMN1; SMN2TDP1 | |
| SCHEMBL1616224 | 0.78 | MAPT (0.55) | MAPTCYP2C9CYP2C19SMN1; SMN2TDP1 | |
| SCHEMBL183414 | 0.77 | MAPT (0.48) | MAPTCYP2C19SMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL3516973 | 0.77 | LMNA (0.45) | MAPTSMN1; SMN2L3MBTL1HTT | |
| SCHEMBL6996715 | 0.76 | APP (0.47) | MAPTCYP2C9CYP2C19SMN1; SMN2TDP1 | |
| SCHEMBL9431930 | 0.76 | L3MBTL1 (0.65) | MAPTCYP2C9CYP2C19SMN1; SMN2TDP1 | |
| SCHEMBL8888358 | 0.75 | LRRK2 (0.63) | MAPTCYP2C9CYP2C19SMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4425362-A | CARDIOVASCULAR DISORDERS, ADRENERGIC BLOCKING AGENTS | SANDOZ LTD. (CH) | 1984-01-10 | — | — | US | disclosed |