Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.62 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.62 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 9/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11805291 | 0.91 | TXNRD1 (0.58) | TXNRD1TXNRD3TXNRD2MAPTNPSR1 | |
| SCHEMBL11067069 | 0.84 | PDE7A (0.45) | TXNRD1TXNRD3TXNRD2MAPTGAA | |
| SCHEMBL8450917 | 0.83 | TXNRD1 (0.70) | TXNRD1TXNRD3TXNRD2MAPTNPSR1 | |
| SCHEMBL13783415 | 0.77 | TXNRD1 (0.62) | TXNRD1TXNRD3TXNRD2MAPTNPSR1 | |
| SCHEMBL30128616 | 0.77 | TXNRD1 (0.78) | TXNRD1TXNRD3TXNRD2MAPTNPSR1 | |
| SCHEMBL1032814 | 0.77 | TXNRD1 (1.00) | TXNRD1TXNRD3TXNRD2MAPTNPSR1 | |
| SCHEMBL6161726 | 0.77 | TXNRD1 (0.78) | TXNRD1TXNRD3TXNRD2MAPTNPSR1 | |
| SCHEMBL11067211 | 0.76 | HSD17B10 (0.47) | NPSR1GAAALDH1A1HSPB1MAPK1 | |
| SCHEMBL3990991 | 0.75 | TXNRD1 (0.75) | TXNRD1TXNRD3TXNRD2MAPTNPSR1 | |
| SCHEMBL11685220 | 0.74 | TXNRD1 (0.72) | TXNRD1TXNRD3TXNRD2MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE31512-E | SISOMICIN BACTERICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1984-01-31 | — | — | US | disclosed |
| EP-0021215-B1 | PSEUDOTRISACCHARIDES, THEIR PREPARATION AND USE AS MEDICAMENTS | BAYER AG (DE) | 1983-07-13 | — | — | EP | disclosed |
| US-4393051-A | BACTERICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1983-07-12 | — | — | US | disclosed |
| US-4380625-A | Process for the preparation of purified aminoglycoside antibiotics | BAYER AKTIENGESELLSCHAFT (DE) | 1983-04-19 | — | — | US | disclosed |
| EP-0032591-B1 | PROCESS FOR THE PREPARATION OF PURIFIED AMINOGLYCOSIDE ANTIBIOTICS | BAYER AG (DE) | 1983-02-02 | — | — | EP | disclosed |
| EP-0007996-B1 | 4,6-DI-0-(AMINOGLYCOSYL)-1,3-DIAMINOCYCLITOLS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BAYER AG (DE) | 1983-01-26 | — | — | EP | disclosed |
| EP-0032591-A1 | Process for the preparation of purified aminoglycoside antibiotics | BAYER AG (DE) | 1981-07-29 | — | — | EP | disclosed |
| US-4235888-A | SISOMYCIN-TYPE ANTIBIOTICS | BAYER AKTIENGESELLSCHAFT (DE) | 1980-11-25 | — | — | US | disclosed |
| US-4190722-A | BACTERICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1980-02-26 | — | — | US | disclosed |
| EP-0007996-A1 | 4,6-Di-0-(Aminoglycosyl)-1,3-diaminocyclitols, process for their preparation and pharmaceutical compositions containing them | BAYER AG (DE) | 1980-02-20 | — | — | EP | disclosed |
| EP-0000057-A1 | Selectively protected 4,6-di-O-(aminoglycosyl)-1,3-diamino-cyclitols | BAYER AG (DE) | 1978-12-20 | — | — | EP | disclosed |