Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KDM4A | O75164 | 1/20 | 0.43 |
| ▸ | TDP2 | O95551 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.41 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.41 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11064622 | 0.84 | TXNRD1 (0.62) | SMN1; SMN2MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL11805291 | 0.81 | TXNRD1 (0.58) | PDE7AMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL11355337 | 0.80 | ALDH1A1 (0.44) | SMN1; SMN2MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL11404352 | 0.78 | ALDH1A1 (0.52) | PDE7ASMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL9321346 | 0.77 | PDE7A (0.55) | PDE7ASMN1; SMN2MEN1KDM4ATDP2 | |
| SCHEMBL24063592 | 0.74 | ALDH1A1 (0.53) | PDE7ASMN1; SMN2MEN1KDM4ATDP2 | |
| SCHEMBL11499701 | 0.74 | PDE7A (0.56) | PDE7ASMN1; SMN2MEN1KDM4ATDP2 | |
| SCHEMBL18928136 | 0.74 | PDE7A (0.51) | PDE7ASMN1; SMN2MEN1KDM4ATDP2 | |
| SCHEMBL11067211 | 0.73 | HSD17B10 (0.47) | PDE7AALDH1A1HTTHSPB1GAA | |
| SCHEMBL3917921 | 0.71 | PDE7A (0.49) | PDE7ASMN1; SMN2MEN1KDM4ATDP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE31512-E | SISOMICIN BACTERICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1984-01-31 | — | — | US | disclosed |
| EP-0021215-B1 | PSEUDOTRISACCHARIDES, THEIR PREPARATION AND USE AS MEDICAMENTS | BAYER AG (DE) | 1983-07-13 | — | — | EP | disclosed |
| US-4393051-A | BACTERICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1983-07-12 | — | — | US | disclosed |
| US-4380625-A | Process for the preparation of purified aminoglycoside antibiotics | BAYER AKTIENGESELLSCHAFT (DE) | 1983-04-19 | — | — | US | disclosed |
| EP-0032591-B1 | PROCESS FOR THE PREPARATION OF PURIFIED AMINOGLYCOSIDE ANTIBIOTICS | BAYER AG (DE) | 1983-02-02 | — | — | EP | disclosed |
| EP-0007996-B1 | 4,6-DI-0-(AMINOGLYCOSYL)-1,3-DIAMINOCYCLITOLS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BAYER AG (DE) | 1983-01-26 | — | — | EP | disclosed |
| EP-0000057-B1 | SELECTIVELY PROTECTED 4,6-DI-O-(AMINOGLYCOSYL)-1,3-DIAMINO-CYCLITOLS | BAYER AG (DE) | 1982-07-14 | — | — | EP | disclosed |
| EP-0032591-A1 | Process for the preparation of purified aminoglycoside antibiotics | BAYER AG (DE) | 1981-07-29 | — | — | EP | disclosed |
| EP-0021215-A1 | Pseudotrisaccharides, their preparation and use as medicaments | BAYER AG (DE) | 1981-01-07 | — | — | EP | disclosed |
| US-4235888-A | SISOMYCIN-TYPE ANTIBIOTICS | BAYER AKTIENGESELLSCHAFT (DE) | 1980-11-25 | — | — | US | disclosed |
| US-4190722-A | BACTERICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1980-02-26 | — | — | US | disclosed |
| EP-0007996-A1 | 4,6-Di-0-(Aminoglycosyl)-1,3-diaminocyclitols, process for their preparation and pharmaceutical compositions containing them | BAYER AG (DE) | 1980-02-20 | — | — | EP | disclosed |
| EP-0000057-A1 | Selectively protected 4,6-di-O-(aminoglycosyl)-1,3-diamino-cyclitols | BAYER AG (DE) | 1978-12-20 | — | — | EP | disclosed |