Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | PDE7A | Q13946 | 9/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.41 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.38 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.38 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11064622 | 0.76 | TXNRD1 (0.62) | HSPB1GAAALDH1A1MAPK1HTT | |
| SCHEMBL11067104 | 0.76 | HSPB1 (0.43) | HSD17B10PDE7AHSPB1GAAALDH1A1 | |
| SCHEMBL10924733 | 0.76 | PDE7A (0.63) | HSD17B10PDE7APDE4BPDE4DPDE7B | |
| SCHEMBL11067069 | 0.73 | PDE7A (0.45) | PDE7AHSPB1GAAALDH1A1CA1 | |
| SCHEMBL11683124 | 0.72 | PDE7A (0.63) | HSD17B10PDE7AHSPB1GAAALDH1A1 | |
| SCHEMBL19981336 | 0.72 | HSPB1 (0.50) | HSD17B10HSPB1GAAALDH1A1CA1 | |
| SCHEMBL11404352 | 0.70 | ALDH1A1 (0.52) | HSD17B10PDE7AHSPB1GAAALDH1A1 | |
| SCHEMBL5406989 | 0.70 | HSD17B10 (0.63) | HSD17B10PDE7AHSPB1ALDH1A1MAPK1 | |
| SCHEMBL11355337 | 0.70 | ALDH1A1 (0.44) | HSPB1GAAALDH1A1HTT | |
| SCHEMBL18914339 | 0.69 | CA1 (0.53) | HSD17B10HSPB1GAAALDH1A1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE31512-E | SISOMICIN BACTERICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1984-01-31 | — | — | US | disclosed |
| EP-0021215-B1 | PSEUDOTRISACCHARIDES, THEIR PREPARATION AND USE AS MEDICAMENTS | BAYER AG (DE) | 1983-07-13 | — | — | EP | disclosed |
| US-4393051-A | BACTERICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1983-07-12 | — | — | US | disclosed |
| US-4380625-A | Process for the preparation of purified aminoglycoside antibiotics | BAYER AKTIENGESELLSCHAFT (DE) | 1983-04-19 | — | — | US | disclosed |
| EP-0032591-B1 | PROCESS FOR THE PREPARATION OF PURIFIED AMINOGLYCOSIDE ANTIBIOTICS | BAYER AG (DE) | 1983-02-02 | — | — | EP | disclosed |
| EP-0007996-B1 | 4,6-DI-0-(AMINOGLYCOSYL)-1,3-DIAMINOCYCLITOLS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BAYER AG (DE) | 1983-01-26 | — | — | EP | disclosed |
| EP-0000057-B1 | SELECTIVELY PROTECTED 4,6-DI-O-(AMINOGLYCOSYL)-1,3-DIAMINO-CYCLITOLS | BAYER AG (DE) | 1982-07-14 | — | — | EP | disclosed |
| EP-0032591-A1 | Process for the preparation of purified aminoglycoside antibiotics | BAYER AG (DE) | 1981-07-29 | — | — | EP | disclosed |
| EP-0021215-A1 | Pseudotrisaccharides, their preparation and use as medicaments | BAYER AG (DE) | 1981-01-07 | — | — | EP | disclosed |
| US-4235888-A | SISOMYCIN-TYPE ANTIBIOTICS | BAYER AKTIENGESELLSCHAFT (DE) | 1980-11-25 | — | — | US | disclosed |
| US-4190722-A | BACTERICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1980-02-26 | — | — | US | disclosed |
| EP-0007996-A1 | 4,6-Di-0-(Aminoglycosyl)-1,3-diaminocyclitols, process for their preparation and pharmaceutical compositions containing them | BAYER AG (DE) | 1980-02-20 | — | — | EP | disclosed |
| EP-0000057-A1 | Selectively protected 4,6-di-O-(aminoglycosyl)-1,3-diamino-cyclitols | BAYER AG (DE) | 1978-12-20 | — | — | EP | disclosed |