Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 3/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | SCN1A | P35498 | 2/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11070251 | 0.83 | ADRB1 (0.44) | ADRB1ADRB2HTR1AOPRK1SCN1A | |
| SCHEMBL11317555 | 0.76 | ADRB1 (0.58) | ADRB1ADRB2HTR1AOPRK1SCN1A | |
| SCHEMBL11317577 | 0.76 | ADRB1 (0.47) | ADRB1ADRB2HTR1AOPRK1SCN1A | |
| SCHEMBL11065776 | 0.71 | ADRB2 (0.40) | ADRB1ADRB2HTR1AOPRK1SCN1A | |
| SCHEMBL9654136 | 0.71 | ADRB1 (0.58) | ADRB1ADRB2HTR1AOPRK1SCN1A | |
| SCHEMBL11069772 | 0.70 | PDE3B (0.50) | ADRB1ADRB2HTR1AOPRK1 | |
| SCHEMBL10593598 | 0.69 | ADRB1 (0.56) | ADRB1ADRB2HTR1AOPRK1SCN1A | |
| SCHEMBL9654133 | 0.69 | ADRB1 (0.61) | ADRB1ADRB2HTR1AOPRK1SCN1A | |
| SCHEMBL11068350 | 0.67 | PDE3B (0.41) | MEN1KMT2ACYP11B2 | |
| SCHEMBL1764193 | 0.67 | ADRB2 (0.57) | ADRB1ADRB2HTR1AOPRK1BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435404-A | ANTICOAGULANTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-03-06 | — | — | US | disclosed |