Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 3/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.38 |
| ▸ | SCN1A | P35498 | 2/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11070251 | 0.88 | ADRB1 (0.44) | ADRB1ADRB2HTR1AOPRK1ATM | |
| SCHEMBL11313435 | 0.85 | ATM (0.41) | ATML3MBTL1PDE3BPDE3AGAA | |
| SCHEMBL11317555 | 0.79 | ADRB1 (0.58) | ADRB1ADRB2HTR1AOPRK1SCN1A | |
| SCHEMBL11359883 | 0.78 | PDE3B (0.48) | PDE3BPDE3ASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL11317207 | 0.77 | PDE3B (0.52) | ADRB1ADRB2HTR1AOPRK1L3MBTL1 | |
| SCHEMBL11061068 | 0.76 | ADRB2 (0.42) | ADRB1ADRB2HTR1AOPRK1PDE3B | |
| SCHEMBL11065568 | 0.76 | ADRB2 (0.42) | ADRB1ADRB2HTR1AOPRK1L3MBTL1 | |
| SCHEMBL11316229 | 0.76 | PDE3B (0.51) | ADRB1ADRB2HTR1AOPRK1PDE3B | |
| SCHEMBL11064885 | 0.76 | ADRB1 (0.44) | ADRB1ADRB2HTR1AOPRK1SCN1A | |
| SCHEMBL11062523 | 0.74 | PDE3B (0.49) | ADRB1ADRB2HTR1AOPRK1PDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4298739-A | ANTICOAGULANTS, ANTIINFLAMMATORY, ANTIULCER, VASODILATOR, PHOSPHODIESTERASE INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1981-11-03 | — | — | US | disclosed |