Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.32 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.32 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.32 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11057482 | 0.88 | HTT (0.38) | RAB9AMAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL11057699 | 0.88 | LDHA (0.35) | SMN1; SMN2RAB9AMAPTKMT2ANPC1 | |
| SCHEMBL11082200 | 0.81 | ELANE (0.32) | ALDH1A1GAA | |
| SCHEMBL11060434 | 0.81 | SMN1; SMN2 (0.34) | SMN1; SMN2RAB9AMAPTKMT2ANPC1 | |
| SCHEMBL11065067 | 0.81 | LOXL2 (0.38) | SMN1; SMN2RAB9AMAPTNPC1ALDH1A1 | |
| SCHEMBL11064901 | 0.80 | TAS1R3 (0.41) | SMN1; SMN2RAB9ANPC1ALDH1A1L3MBTL1 | |
| SCHEMBL11088045 | 0.78 | HPGD (0.43) | SMN1; SMN2RAB9AKMT2ANPC1ALDH1A1 | |
| SCHEMBL11062135 | 0.78 | TSHR (0.44) | SMN1; SMN2MAPTKMT2AALDH1A1L3MBTL1 | |
| SCHEMBL11086105 | 0.77 | DYRK1A (0.31) | ALDH1A1 | |
| SCHEMBL11061784 | 0.77 | PADI1 (0.39) | SMN1; SMN2RAB9AMAPTKMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4458081-A | ANTIINFLAMMATORY, ANALGESIC, ANTICOAGULANT, MUSCLE RELAXANT | SYNTEX (U.S.A.) INC. (US) | 1984-07-03 | — | — | US | disclosed |
| US-4454326-A | 5-Aroyl 6-chloro or 6-bromo 1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1,1-di-carboxylates | SYNTEX (U.S.A.) INC. (US) | 1984-06-12 | — | — | US | disclosed |
| US-4347187-A | Process for preparing 5-aroyl 1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic acids and novel intermediates therein | SYNTEX (U.S.A.) INC. (US) | 1982-08-31 | — | — | US | disclosed |
| US-4347186-A | Process for preparing 5-aroyl 1,2-dihydro-3-H pyrrolo[1,2-a]pyrrole-1-carboxylic acids and novel intermediates therein | SYNTEX (U.S.A.) INC. (US) | 1982-08-31 | — | — | US | disclosed |