Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOD1 | P00441 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | HTR1A | P08908 | 6/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11065682 | 0.99 | KMT2A (0.51) | SOD1KMT2AALDH1A1MAPTHTR1A | |
| SCHEMBL11068893 | 0.91 | ALDH1A1 (0.52) | KMT2AALDH1A1MAPTHTR1AHTT | |
| SCHEMBL11066025 | 0.81 | HTR1A (0.50) | KMT2AALDH1A1HTR1ATSHRDRD2 | |
| SCHEMBL11362858 | 0.81 | MAPT (0.53) | SOD1KMT2AALDH1A1MAPTHTR1A | |
| SCHEMBL11068301 | 0.73 | MEN1 (0.54) | KMT2AHTR1ATSHRDRD2MEN1 | |
| SCHEMBL11073463 | 0.73 | KCNH2 (0.55) | ALDH1A1HTR1ALMNASIGMAR1 | |
| SCHEMBL11068915 | 0.73 | DRD2 (0.60) | KMT2AALDH1A1HTR1ALMNATSHR | |
| SCHEMBL11075146 | 0.73 | SMN1; SMN2 (0.62) | KMT2ASIGMAR1MEN1POLB | |
| Hydrochloric Acid SCHEMBL11066446 | 0.72 | DRD2 (0.59) | KMT2AALDH1A1HTR1ALMNATSHR | |
| Hydrochloric Acid SCHEMBL11066381 | 0.72 | SMN1; SMN2 (0.64) | KMT2ASIGMAR1MEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4443462-A | Antipsychotic 4-(naphthalenyloxy)piperidine derivatives | MERRELL DOW PHARMACEUTICALS INC. (US) | 1984-04-17 | — | — | US | disclosed |