Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | HTR1A | P08908 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.51 |
| ▸ | DRD1 | P21728 | 1/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.51 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11066025 | 0.91 | HTR1A (0.50) | ALDH1A1POLBHTR1AKMT2AMEN1 | |
| SCHEMBL11065103 | 0.91 | SOD1 (0.51) | ALDH1A1POLBHTR1AKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL11065682 | 0.90 | KMT2A (0.51) | ALDH1A1POLBHTR1AKMT2AMEN1 | |
| SCHEMBL11068301 | 0.82 | MEN1 (0.54) | HTR1AKMT2AMEN1CHRM2ADRA2A | |
| SCHEMBL11068915 | 0.82 | DRD2 (0.60) | ALDH1A1POLBHTR1AKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL11066446 | 0.81 | DRD2 (0.59) | ALDH1A1POLBHTR1AKMT2AMEN1 | |
| SCHEMBL11069216 | 0.76 | CHRM2 (0.56) | ALDH1A1POLBHTR1AKMT2AMEN1 | |
| SCHEMBL6348978 | 0.76 | ALDH1A1 (0.57) | ALDH1A1POLBHTR1AKMT2AMEN1 | |
| SCHEMBL11759007 | 0.74 | ALDH1A1 (0.87) | ALDH1A1POLBHTR1AKMT2AADRA1A | |
| SCHEMBL11073463 | 0.74 | KCNH2 (0.55) | ALDH1A1HTR1AADRA1AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4443462-A | Antipsychotic 4-(naphthalenyloxy)piperidine derivatives | MERRELL DOW PHARMACEUTICALS INC. (US) | 1984-04-17 | — | — | US | disclosed |