Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 8/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.42 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11165675 | 0.86 | MAPT (0.43) | MAPK1MAPTALDH1A1HTTALDH3A1 | |
| SCHEMBL11169184 | 0.85 | ALDH1A1 (0.43) | PTGS1ALDH1A1HTTRAB9ANPC1 | |
| SCHEMBL11060669 | 0.84 | MAPK1 (0.45) | CHRM1PTGS1MAPK1MAPTALDH1A1 | |
| SCHEMBL11167920 | 0.82 | CHRM1 (0.40) | CHRM1PTGS1MAPK1MAPTALDH1A1 | |
| SCHEMBL11042080 | 0.80 | MAPK1 (0.43) | MAPK1MAPTALDH1A1HTTALDH3A1 | |
| SCHEMBL11170500 | 0.73 | MAPK1 (0.47) | MAPK1MAPTALDH1A1HTTRAB9A | |
| SCHEMBL12316376 | 0.72 | HSP90AA1 (0.51) | MAPK1MAPTALDH1A1HTTALDH3A1 | |
| SCHEMBL10957987 | 0.71 | SMN1; SMN2 (0.51) | MAPK1MAPTALDH1A1HTTALDH3A1 | |
| SCHEMBL11165251 | 0.70 | MAPT (0.41) | MAPK1MAPTALDH1A1HTTRAB9A | |
| SCHEMBL29688382 | 0.70 | PKM (0.42) | MAPK1MAPTALDH1A1HTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0082109-A2 | Substituted 2-hydroxyphenylacetic acids and derivatives of them | CIBA-GEIGY AG (CH) | 1983-06-22 | — | — | EP | claimed |
| US-4480106-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, LIGHT STABILIZERS | CIBA-GEIGY CORPORATION (US) | 1984-10-30 | — | — | US | disclosed |
| EP-0082109-A2 | Substituted 2-hydroxyphenylacetic acids and derivatives of them | CIBA-GEIGY AG (CH) | 1983-06-22 | — | — | EP | disclosed |
| EP-0078239-A2 | Process for preparing asymmetrically substituted maleic-acid anhydrides, and asymmetrically substituted maleic acid anhydrides | CIBA-GEIGY AG (CH) | 1983-05-04 | — | — | EP | disclosed |