Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.40 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | ACP1 | P24666 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8818395 | 0.79 | ALDH1A1 (0.53) | ALDH1A1L3MBTL1TSHRKMT2AMEN1 | |
| SCHEMBL9710144 | 0.79 | GPR35 (0.46) | ALDH1A1L3MBTL1GPR35TSHRCA12 | |
| SCHEMBL4872833 | 0.79 | ALDH1A1 (0.53) | ALDH1A1L3MBTL1TSHRKMT2AMEN1 | |
| SCHEMBL27825182 | 0.79 | CTSB (0.36) | ALDH1A1CA12KMT2AMEN1TDP1 | |
| SCHEMBL981024 | 0.78 | KMT2A (0.41) | PRMT5WDR77ALDH1A1GPR35KMT2A | |
| SCHEMBL1787921 | 0.78 | KMT2A (0.41) | PRMT5WDR77ALDH1A1GPR35KMT2A | |
| SCHEMBL9654903 | 0.78 | PRMT5 (0.40) | PRMT5WDR77ALDH1A1GPR35TSHR | |
| SCHEMBL336604 | 0.78 | KMT2A (0.41) | PRMT5WDR77ALDH1A1GPR35KMT2A | |
| SCHEMBL981027 | 0.78 | KMT2A (0.41) | PRMT5WDR77ALDH1A1GPR35KMT2A | |
| SCHEMBL6223771 | 0.78 | PRMT5 (0.40) | PRMT5WDR77ALDH1A1GPR35TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4438107-A | Aminoglycosides and use thereof | KOWA COMPANY, LTD. (JP) | 1984-03-20 | — | — | US | disclosed |
| EP-0071251-A1 | Novel aminoglycosides and use thereof | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1983-02-09 | — | — | EP | disclosed |