Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | APEX1 | P27695 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | LIPE | Q05469 | 4/20 | 0.46 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.43 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.43 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30434705 | 0.89 | MAPK1 (0.58) | MAPK1LMNACYP2C9TSHRAPEX1 | |
| SCHEMBL11307569 | 0.81 | MAPK1 (0.69) | MAPK1LMNACYP2C9TSHRAPEX1 | |
| SCHEMBL2476407 | 0.77 | LMNA (0.67) | MAPK1LMNACYP2C9TSHRAPEX1 | |
| SCHEMBL8969033 | 0.77 | AR (0.49) | MAPK1LMNATSHRSMN1; SMN2KMT2A | |
| SCHEMBL10953337 | 0.77 | LMNA (0.58) | MAPK1LMNACYP2C9TSHRAPEX1 | |
| SCHEMBL4348260 | 0.76 | SLC6A4 (0.54) | LMNACYP2C9KMT2AMAPTMEN1 | |
| SCHEMBL10997903 | 0.74 | CYP1A2 (0.44) | MAPK1LMNACYP2C9TSHRAPEX1 | |
| SCHEMBL28479796 | 0.74 | POLB (0.43) | MAPK1LMNACYP2C9TSHRAPEX1 | |
| SCHEMBL2365611 | 0.74 | PPARG (0.63) | MAPK1LMNACYP2C9TSHRAPEX1 | |
| SCHEMBL240269 | 0.74 | SMN1; SMN2 (1.00) | MAPK1LMNACYP2C9TSHRAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4443247-A | HERBICIDES, PLANT GROWTH REGULATORS | CIBA-GEIGY CORPORATION (US) | 1984-04-17 | — | — | US | disclosed |
| US-4433998-A | Pyridyloxy-phenoxyalkanecarboxylic acid derivatives and their herbicidal use | CIBA-GEIGY CORPORATION (US) | 1984-02-28 | — | — | US | disclosed |
| US-4425157-A | Pyridyloxy-phenoxy-alkanethiocarboxylic acid ester derivatives and their herbicidal use | CIBA-GEIGY CORPORATION (US) | 1984-01-10 | — | — | US | disclosed |
| US-4384882-A | HERBICIDES, PLANT GROWTH REGULATORS | CIBA-GEIGY CORPORATION (US) | 1983-05-24 | — | — | US | disclosed |
| US-4329167-A | HERBICIDES, PLANT GROWTH REGULATORS | CIBA-GEIGY CORPORATION (US) | 1982-05-11 | — | — | US | disclosed |