Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PTPRZ1 | P23471 | 3/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KCNK2 | O95069 | 2/20 | 0.34 |
| ▸ | KCNK10 | P57789 | 2/20 | 0.34 |
| ▸ | TERT | O14746 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.32 |
| ▸ | ERN1 | O75460 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15697534 | 0.80 | ALDH1A1 (0.39) | ALDH1A1TDP1KDM4EPTPRZ1PTPN1 | |
| SCHEMBL26635431 | 0.79 | ALDH1A1 (0.38) | ALDH1A1TDP1KDM4EPTPRZ1PTPN1 | |
| SCHEMBL10916030 | 0.79 | ERN1 (0.47) | ALDH1A1TDP1KDM4EMAPTLMNA | |
| SCHEMBL6894572 | 0.76 | ALDH1A1 (0.47) | ALDH1A1TDP1KDM4ESMN1; SMN2MAPT | |
| SCHEMBL7819802 | 0.75 | ALDH1A1 (0.46) | ALDH1A1TDP1KDM4ESMN1; SMN2MAPT | |
| SCHEMBL13844433 | 0.72 | TDP1 (0.35) | ALDH1A1TDP1TERTVCAM1ERN1 | |
| SCHEMBL9182158 | 0.72 | VCAM1 (0.47) | ALDH1A1TDP1MAPTLMNATSHR | |
| SCHEMBL132042 | 0.72 | ALDH1A1 (0.41) | ALDH1A1TDP1TSHR | |
| SCHEMBL10941731 | 0.72 | ALDH1A1 (0.42) | ALDH1A1TDP1KDM4EPTPRZ1PTPN1 | |
| SCHEMBL27876484 | 0.72 | ALDH1A1 (0.45) | ALDH1A1TDP1KDM4EPTPRZ1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4431808-A | ANTIDEPRESSANTS; TRANQUILIZERS; NEUROLEPTIC AGENTS | SPOFA, SPOJENE PODNIKY PRO ZDRAVOTNICKOU VYROBU (CS) | 1984-02-14 | — | — | US | disclosed |