Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.85 |
| ▸ | MEN1 | O00255 | 2/20 | 0.85 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 4/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | MAOA | P21397 | 4/20 | 0.53 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9302685 | 0.92 | MEN1 (1.00) | KMT2AMEN1HSD17B10SMN1; SMN2LMNA | |
| SCHEMBL5623889 | 0.86 | MEN1 (0.88) | KMT2AMEN1HSD17B10SMN1; SMN2LMNA | |
| SCHEMBL16724735 | 0.83 | MEN1 (0.58) | KMT2AMEN1SMN1; SMN2LMNAMAOA | |
| SCHEMBL19439086 | 0.83 | MEN1 (0.81) | KMT2AMEN1HSD17B10SMN1; SMN2LMNA | |
| SCHEMBL8945706 | 0.83 | MEN1 (0.81) | KMT2AMEN1HSD17B10SMN1; SMN2LMNA | |
| SCHEMBL12928357 | 0.83 | MEN1 (0.81) | KMT2AMEN1HSD17B10SMN1; SMN2LMNA | |
| SCHEMBL10013782 | 0.83 | MEN1 (0.81) | KMT2AMEN1HSD17B10SMN1; SMN2LMNA | |
| SCHEMBL11065585 | 0.83 | KMT2A (0.58) | KMT2AMEN1HSD17B10SMN1; SMN2LMNA | |
| SCHEMBL2531879 | 0.83 | MEN1 (0.81) | KMT2AMEN1HSD17B10SMN1; SMN2LMNA | |
| SCHEMBL5623546 | 0.82 | MEN1 (0.81) | KMT2AMEN1HSD17B10SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9567307-B2 | Amination of aryl alcohol derivatives | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-02-14 | — | — | US | disclosed |
| US-9567307-B2 | Amination of aryl alcohol derivatives | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-02-14 | — | — | US | disclosed |
| EP-2997049-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | Basell Poliolefine Italia S.r.l. (IT) | 2016-03-23 | — | — | EP | disclosed |
| WO-2014184289-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2014-11-20 | — | — | WO | disclosed |
| US-20130289270-A1 | Amination of Aryl Alcohol Derivatives | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-10-31 | — | — | US | disclosed |
| US-20130289270-A1 | Amination of Aryl Alcohol Derivatives | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-10-31 | — | — | US | disclosed |
| US-20100305100-A1 | METHODS FOR TREATING HEPATITIS C | PTC THERAPEUTICS, INC. (US) | 2010-12-02 | — | — | US | disclosed |
| US-5510375-A | VIRICIDES TREATING INFECTION CAUSED BY HUMAN IMMUNODEFICIENCY VIRUS AND AIDS | WARNER-LAMBERT COMPANY (US) | 1996-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100305100-A1 | METHODS FOR TREATING HEPATITIS C | HAVCR2, EIF2AK2, MAVS | KMT2A 4464/4885MEN1 4800/4885HSD17B10 1276/4885 |
| US-20130289270-A1 | Amination of Aryl Alcohol Derivatives | SULT2A1, SULT1A1, ADH5 | KMT2A 122/4885MEN1 4461/4885HSD17B10 1183/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.