Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MMP13 | P45452 | 4/20 | 0.43 |
| ▸ | MMP2 | P08253 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11075982 | 0.86 | KDM4E (0.46) | KDM4EALDH1A1HPGDHSD17B10MAPK1 | |
| SCHEMBL11069218 | 0.78 | KDM4E (0.48) | KDM4EALDH1A1HPGDHSD17B10MAPK1 | |
| SCHEMBL11260822 | 0.78 | ALDH1A1 (0.36) | KDM4EALDH1A1HPGDHSD17B10MAPK1 | |
| SCHEMBL11064412 | 0.75 | GABRA1 (0.60) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL9724289 | 0.75 | ALDH1A1 (0.68) | KDM4EALDH1A1HPGDHSD17B10MAPK1 | |
| SCHEMBL10478330 | 0.73 | ALOX15 (0.49) | KDM4EALDH1A1HPGDHSD17B10MAPK1 | |
| SCHEMBL9452276 | 0.73 | KDM4E (0.48) | KDM4EALDH1A1HPGDHSD17B10MAPK1 | |
| SCHEMBL5565082 | 0.73 | KDM4E (0.62) | KDM4EALDH1A1HPGDHSD17B10MAPK1 | |
| SCHEMBL31437284 | 0.73 | KDM4E (0.62) | KDM4EALDH1A1HPGDHSD17B10MAPK1 | |
| SCHEMBL5639156 | 0.73 | ALOX15 (0.69) | KDM4EALDH1A1HPGDHSD17B10MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4476132-A | Acylquinolinone derivatives, and antiallergic preparations and methods of inhibiting allergic reactions using them | CIBA-GEIGY CORPORATION (US) | 1984-10-09 | — | — | US | disclosed |