Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NGFR | P08138 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | GPR35 | Q9HC97 | 4/20 | 0.46 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.46 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | AHR | P35869 | 1/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11065628 | 0.86 | KDM4E (0.47) | KDM4EMEN1HPGDMAPK1KMT2A | |
| SCHEMBL11260822 | 0.81 | ALDH1A1 (0.36) | KDM4EHPGDMAPK1KMT2ALMNA | |
| SCHEMBL11065167 | 0.78 | GPR35 (0.64) | KDM4EMEN1HPGDMAPK1KMT2A | |
| SCHEMBL11064032 | 0.76 | GPR35 (0.52) | KDM4EMEN1HPGDMAPK1KMT2A | |
| SCHEMBL17204921 | 0.76 | GPR35 (0.51) | KDM4EMEN1HPGDMAPK1KMT2A | |
| SCHEMBL2905349 | 0.76 | MEN1 (0.59) | KDM4EMEN1HPGDMAPK1KMT2A | |
| SCHEMBL10809974 | 0.74 | ALDH1A1 (0.41) | KDM4EHPGDMAPK1LMNAALDH1A1 | |
| SCHEMBL11643685 | 0.74 | GPR35 (0.65) | KDM4EMEN1HPGDMAPK1KMT2A | |
| SCHEMBL11071730 | 0.73 | GABRA1 (0.53) | KDM4EMEN1HPGDKMT2ACYP2C9 | |
| SCHEMBL11267548 | 0.70 | PIN1 (0.50) | MEN1HPGDKMT2ALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4476132-A | Acylquinolinone derivatives, and antiallergic preparations and methods of inhibiting allergic reactions using them | CIBA-GEIGY CORPORATION (US) | 1984-10-09 | — | — | US | disclosed |