Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 3/20 | 0.42 |
| ▸ | F3 | P13726 | 3/20 | 0.42 |
| ▸ | MMP2 | P08253 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ECE1 | P42892 | 1/20 | 0.42 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.42 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.42 |
| ▸ | MUS81 | Q96NY9 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 7/20 | 0.42 |
| ▸ | CES1 | P23141 | 3/20 | 0.42 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.42 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.40 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11065692 | 1.00 | F7 (0.42) | F7F3MMP2MAPTKDM4E | |
| SCHEMBL11070645 | 0.90 | FAAH (0.41) | F7F3MMP2MAPTKDM4E | |
| SCHEMBL11070648 | 0.90 | FAAH (0.41) | F7F3MMP2MAPTKDM4E | |
| SCHEMBL11070777 | 0.88 | SOAT2 (0.40) | MAPTFAAHCES1SOAT2SOAT1 | |
| SCHEMBL11503194 | 0.84 | ALDH1A1 (0.40) | F7F3MMP2MAPTKDM4E | |
| SCHEMBL11070793 | 0.81 | FAAH (0.37) | F7F3MMP2MAPTKDM4E | |
| SCHEMBL11070795 | 0.81 | FAAH (0.37) | F7F3MMP2MAPTKDM4E | |
| SCHEMBL11492542 | 0.79 | FAAH (0.44) | F7F3MMP2MAPTKDM4E | |
| SCHEMBL11492543 | 0.79 | FAAH (0.44) | F7F3MMP2MAPTKDM4E | |
| SCHEMBL5514063 | 0.76 | NPC1 (0.51) | KDM4EALDH1A1TP53NPC1JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4440940-A | HYPOLIPIDEMIC AND ANTIATHEROSCLEROTIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1984-04-03 | — | — | US | disclosed |