Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 6/20 | 0.37 |
| ▸ | MGLL | Q99685 | 3/20 | 0.37 |
| ▸ | CES1 | P23141 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.35 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | PLA2G4C | Q9UP65 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.33 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 2/20 | 0.31 |
| ▸ | F7 | P08709 | 2/20 | 0.31 |
| ▸ | F3 | P13726 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11070793 | 1.00 | FAAH (0.37) | FAAHMGLLCES1ALDH1A1MAPT | |
| SCHEMBL11488677 | 0.83 | FAAH (0.38) | FAAHMGLLCES1ALDH1A1MAPT | |
| SCHEMBL11488679 | 0.83 | FAAH (0.38) | FAAHMGLLCES1ALDH1A1MAPT | |
| SCHEMBL11065689 | 0.81 | F7 (0.42) | FAAHMGLLCES1ALDH1A1MAPT | |
| SCHEMBL11065692 | 0.81 | F7 (0.42) | FAAHMGLLCES1ALDH1A1MAPT | |
| SCHEMBL11070648 | 0.80 | FAAH (0.41) | FAAHMGLLCES1ALDH1A1MAPT | |
| SCHEMBL11070645 | 0.80 | FAAH (0.41) | FAAHMGLLCES1ALDH1A1MAPT | |
| SCHEMBL11070777 | 0.79 | SOAT2 (0.40) | FAAHMGLLCES1ALDH1A1MAPT | |
| SCHEMBL11070644 | 0.75 | MLYCD (0.40) | FAAHALDH1A1MAPT | |
| SCHEMBL11503194 | 0.74 | ALDH1A1 (0.40) | FAAHMGLLCES1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4440940-A | HYPOLIPIDEMIC AND ANTIATHEROSCLEROTIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1984-04-03 | — | — | US | disclosed |