SCHEMBL11065802

SCHEMBL11065802

C=CCN(C(C)c1ccccc1)S(=O)(=O)c1ccc(C(=O)N(C)C)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAS2R14 Q9NYV8 1/20 0.49
DAGLA Q9Y4D2 1/20 0.47
LIMK2 P53671 3/20 0.46
OPRD1 P41143 2/20 0.46
ALDH1A1 P00352 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
GAA P10253 1/20 0.44
RAB9A P51151 1/20 0.43
CCR5 P51681 1/20 0.42
PDK1 Q15118 4/20 0.41
HSD11B1 P28845 1/20 0.41
ESR1 P03372 1/20 0.41
C5AR1 P21730 1/20 0.39
MMP2 P08253 1/20 0.38
MMP9 P14780 1/20 0.38
MMP8 P22894 1/20 0.38
MMP13 P45452 1/20 0.38
MEN1 O00255 1/20 0.38
MAPT P10636 1/20 0.38
HPGD P15428 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11060281 0.87 TAS2R14 (0.50) TAS2R14DAGLALIMK2ALDH1A1SMN1; SMN2
SCHEMBL11436521 0.85 DAGLA (0.47) TAS2R14DAGLASMN1; SMN2GAARAB9A
SCHEMBL11067166 0.84 ESR1 (0.58) TAS2R14DAGLARAB9ACCR5ESR1
SCHEMBL11063373 0.79 CNR2 (0.46) TAS2R14DAGLACCR5ESR1C5AR1
SCHEMBL11442725 0.77 S1PR1 (0.44) TAS2R14DAGLARAB9AESR1C5AR1
SCHEMBL7704844 0.75 TSHR (0.39) TAS2R14DAGLARAB9ACCR5ESR1
SCHEMBL11062327 0.73 C5AR1 (0.38) TAS2R14DAGLARAB9AHSD11B1ESR1
SCHEMBL11439451 0.69 S1PR1 (0.41) RAB9ACCR5ESR1C5AR1MAPT
SCHEMBL19471016 0.69 DAGLA (0.70) TAS2R14DAGLAMMP2MMP9MMP8
SCHEMBL17674720 0.69 DAGLA (0.70) TAS2R14DAGLAMMP2MMP9MMP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4468245-A N-(2,3-Epoxypropylene)-n-aralkylsulfonamide and herbicidal compositions containing the same MITSUBISHI CHEMICAL INDUSTRIES LTD. (JP) 1984-08-28 US disclosed