SCHEMBL11062327

SCHEMBL11062327

C=CCN(C(C)c1ccccc1)S(=O)(=O)c1ccccc1C

nearest known ligand 0.38

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
C5AR1 P21730 1/20 0.38
DAGLA Q9Y4D2 1/20 0.36
KMT2A Q03164 3/20 0.36
HSD11B1 P28845 1/20 0.36
RAB9A P51151 1/20 0.36
MAPT P10636 2/20 0.35
MEN1 O00255 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
ESR1 P03372 1/20 0.35
TAS2R14 Q9NYV8 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
HTR2A P28223 1/20 0.34
HTR2C P28335 1/20 0.34
S1PR1 P21453 1/20 0.34
POLB P06746 2/20 0.34
KDM4E B2RXH2 1/20 0.34
HCRTR2 O43614 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11436521 0.83 DAGLA (0.47) C5AR1DAGLAKMT2ARAB9AMAPT
SCHEMBL7704844 0.81 TSHR (0.39) C5AR1DAGLAKMT2ARAB9AMEN1
SCHEMBL11067166 0.77 ESR1 (0.58) C5AR1DAGLARAB9AESR1TAS2R14
SCHEMBL28185888 0.76 RAB9A (0.48) C5AR1KMT2ARAB9AMAPTMEN1
SCHEMBL11442725 0.75 S1PR1 (0.44) C5AR1DAGLARAB9AESR1TAS2R14
SCHEMBL11063373 0.74 CNR2 (0.46) C5AR1DAGLAESR1TAS2R14HTR2A
SCHEMBL11060281 0.74 TAS2R14 (0.50) C5AR1DAGLAKMT2ARAB9AMAPT
SCHEMBL11065802 0.73 TAS2R14 (0.49) C5AR1DAGLAKMT2AHSD11B1RAB9A
SCHEMBL5576296 0.73 C5AR1 (0.42) C5AR1KMT2AHSD11B1RAB9AMAPT
SCHEMBL1137366 0.69 HTR2A (0.39) HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4468245-A N-(2,3-Epoxypropylene)-n-aralkylsulfonamide and herbicidal compositions containing the same MITSUBISHI CHEMICAL INDUSTRIES LTD. (JP) 1984-08-28 US disclosed